ArticleProceedings of the National Academy of Sciences of the United States of America2000
Dictyostelium amoebae lacking an F-box protein form spores rather than stalk in chimeras with wild type.
Article in Proceedings of the National Academy of Sciences of the United States of America, 2000. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 54 papers.
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Who cites it
54 citing papers in PubMed.
- Protist oxygen-sensing and the role of prolyl hydroxylase-regulation of E3(SCF) ubiquitin ligases.Biochimica et biophysica acta. General subjects · 2026Review
- Aggregative chimeric multicellularity in the absence of lethal kin discrimination.The ISME journal · 2026Article
- Going against the family: Perturbation of a greenbeard pathway leads to falsebeard cheating.iScience · 2024Article
- The greenbeard gene tgrB1 regulates altruism and cheating in Dictyostelium discoideum.Nature communications · 2024Article
- In the social amoebaPeerJ · 2024Article
- Parallel evolution of the G protein-coupled receptor GrlG and the loss of fruiting body formation in the social amoeba Dictyostelium discoideum evolved under low relatedness.G3 (Bethesda, Md.) · 2023Article
- Reduced social function in experimentally evolvedProceedings. Biological sciences · 2023Article
- Article
- Review
- Synergy between a cytoplasmic vWFA/VIT protein and a WD40-repeat F-box protein controls development inFrontiers in cell and developmental biology · 2023Article
- Autophagy of the somatic stalk cells likely nurses the propagating spores of Dictyostelid social amoebas.Open research Europe · 2022Article
- WildEcology and evolution · 2020Article
- Article
- Cellular allorecognition and its roles in Dictyostelium development and social evolution.The International journal of developmental biology · 2019Review
- Nonclonal coloniality: Genetically chimeric colonies through fusion of sexually produced polyps in the hydrozoanEvolution letters · 2018Article
- Genetic signatures of microbial altruism and cheating in social amoebas in the wild.Proceedings of the National Academy of Sciences of the United States of America · 2018Article
- G-Protein Dependent Signal Transduction and Ubiquitination in Dictyostelium.International journal of molecular sciences · 2017Review
- Article
- Temporal regulation of kin recognition maintains recognition-cue diversity and suppresses cheating.Nature communications · 2015Article
- Sociogenomics of self vs. non-self cooperation during development of Dictyostelium discoideum.BMC genomics · 2014Article
Corrections and comments
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Authors and funding
4 authors.
Funding
Abstract
Using a selection for Dictyostelium mutants that preferentially form spores, we have recovered a mutant called CheaterA. In chimeras with isogenic wild-type cells, the CheaterA mutant preferentially forms viable spores rather than inviable stalk cells. The mutant causes wild-type cells that have begun to express spore-specific genes to accumulate in the prestalk compartment of the developing organism. In the wild-type cells, the chtA transcript is absent in growing cells and appears early in development. No transcript was detected in the mutant by Northern blot. The chtA gene codes for a protein with an F-box and WD40 domains. This class of protein usually forms part of an Skp1, cullin, F-box (SCF) complex that targets specific protein substrates for ubiquitination and degradation.
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