Evidence map›Paper›PMID 10712422›Full record

ArticleThe Journal of clinical investigation2000

Egr-1: is it always immediate and early?

S F Yan, D J Pinsky, N Mackman, D M Stern

Abstract readComment
In one paragraph

Article in The Journal of clinical investigation, 2000. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed.

  1. Underlying Genes Involved in Atherosclerotic Macrophages: Insights from Microarray Data Mining.Medical science monitor : international medical journal of experimental and clinical research · 2019
    Article
  2. Review
  3. Article
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  5. Article
  6. Review
  7. Article
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  14. Identifying targets for COPD treatment through gene expression analyses.International journal of chronic obstructive pulmonary disease · 2008
    Review
  15. Article
  16. Cigarette smoke stimulates matrix metalloproteinase-2 activity via EGR-1 in human lung fibroblasts.American journal of respiratory cell and molecular biology · 2007
    Article
  17. Article
  18. Comprehensive gene expression profiles reveal pathways related to the pathogenesis of chronic obstructive pulmonary disease.Proceedings of the National Academy of Sciences of the United States of America · 2004
    Article
  19. Endothelium, inflammation, and diabetes.Current diabetes reports · 2002
    Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

4 authors.

S F YanDepartments of Surgery, Medicine, and Physiology and Cellular Biophysics, College of Physicians and Surgeons of Columbia University, New York, New York 10032, USA. sy18@columbia.edu
D J Pinsky
N Mackman
D M Stern

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

AnimalsArteriosclerosisDNA-Binding ProteinsEarly Growth Response Protein 1Endothelium, VascularHumansImmediate-Early ProteinsIschemiaMiceMice, KnockoutPlatelet-Derived Growth FactorThromboplastinTranscription FactorsZinc FingersDNA-Binding ProteinsEarly Growth Response Protein 1EGR1 protein, humanEgr1 protein, mouseImmediate-Early ProteinsPlatelet-Derived Growth FactorThromboplastinTranscription Factors

Identifiers

PMID10712422
PMCPMC292461

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.