Evidence map›Paper›PMID 10710415›Full record

ReviewNucleic acids research2000

SURVEY AND SUMMARY: Saccharomyces cerevisiae basic helix-loop-helix proteins regulate diverse biological processes.

K A Robinson, J M Lopes

Open access · bronzeAbstract readReview
In one paragraph

Review in Nucleic acids research, 2000. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 61 papers.

0numbers the graph read from it
0cells of the map it votes in
61citing papers in PubMed
1.6field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

61 citing papers in PubMed, 119 citations in OpenAlex.

  1. Article
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  5. Review
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  8. The dual role of SrbA from Paracoccidioides lutzii: a hypoxic regulator.Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology] · 2021
    Article
  9. Article
  10. Frontiers in plant science · 2020
    Article
  11. Review
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  13. Review
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Article

1 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

K A RobinsonDepartment of Molecular and Cellular Biochemistry, Loyola University of Chicago, Maywood, IL 60153, USA.
J M Lopes
University of Chicago · US

Funding

HSRD VA TPP 97-002
6 · The paper itself

Abstract

Basic helix-loop-helix (bHLH) proteins are among the most well studied and functionally important regulatory proteins in all eukaryotes. The HLH domain dictates dimerization to create homo- and heterodimers. Dimerization juxtaposes the basic regions of the two monomers to create a DNA interaction surface that recognizes the consensus sequence called the E-box, 5'-CANNTG-3'. Several bHLH proteins have been identified in the yeast Saccharomyces cerevisiae using traditional genetic methodologies. These proteins regulate diverse biological pathways. The completed sequence of the yeast genome, combined with novel methodologies allowing whole-genome expression studies, now offers a unique opportunity to study the function of these bHLH proteins. It is the purpose of this review to summarize the current knowledge of bHLH protein function in yeast.

Indexed as

Repressor ProteinsSaccharomyces cerevisiae ProteinsTrans-ActivatorsAmino Acid SequenceBasic Helix-Loop-Helix Leucine Zipper Transcription FactorsBasic Helix-Loop-Helix ProteinsDNA-Binding ProteinsFungal ProteinsGenes, FungalHelix-Loop-Helix MotifsSaccharomyces cerevisiaeSequence Homology, Amino AcidTranscription FactorsBasic Helix-Loop-Helix Leucine Zipper Transcription FactorsBasic Helix-Loop-Helix ProteinsCBF1 protein, S cerevisiaeDNA-Binding ProteinsFungal ProteinsINO2 protein, S cerevisiaeINO4 protein, S cerevisiaePHO4 protein, S cerevisiaeRepressor ProteinsRTG1 protein, S cerevisiaeRTG3 protein, S cerevisiaeSaccharomyces cerevisiae ProteinsTrans-ActivatorsTranscription FactorsTYE7 protein, S cerevisiae

Identifiers

PMID10710415
PMCPMC102793
OpenAlexW2010485309

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.