ArticleLearning & memory (Cold Spring Harbor, N.Y.)2000
Tissue-specific expression of a type I adenylyl cyclase rescues the rutabaga mutant memory defect: in search of the engram.
Article in Learning & memory (Cold Spring Harbor, N.Y.), 2000. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 68 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
68 citing papers in PubMed, 144 citations in OpenAlex.
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- Neuronal circuit mechanisms of competitive interaction between action-based and coincidence learning.Science advances · 2024Article
- HoTDAM! An easy-to-use automated assay expands the inducible thermotolerance phenotype in Drosophila melanogaster: Heat hardening reduces motility.Comparative biochemistry and physiology. Part A, Molecular & integrative physiology · 2023Article
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- A high-performance genetically encoded fluorescent indicator for in vivo cAMP imaging.Nature communications · 2022Article
- Rest Is Required to Learn an Appetitively-Reinforced Operant Task inFrontiers in behavioral neuroscience · 2021Article
- Serotonin receptor 5-HT7 in Drosophila mushroom body neurons mediates larval appetitive olfactory learning.Scientific reports · 2020Article
- Evolutionarily Conserved Regulation of Sleep by the Protein Translational Regulator PERK.Current biology : CB · 2020Article
- Finding a place and leaving a mark in memory formation.Journal of neurogenetics · 2020Review
- Cellular and circuit mechanisms of olfactory associative learning inJournal of neurogenetics · 2020Review
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- Multiple genetic loci affect place learning and memory performance in Drosophila melanogaster.Genes, brain, and behavior · 2019Article
- Distinct Dopamine Receptor Pathways Underlie the Temporal Sensitivity of Associative Learning.Cell · 2019Article
- NewG3 (Bethesda, Md.) · 2019Article
- An Automated Method to Determine the Performance of Drosophila in Response to Temperature Changes in Space and Time.Journal of visualized experiments : JoVE · 2018Article
- Place learning overrides innate behaviors inLearning & memory (Cold Spring Harbor, N.Y.) · 2018Article
- The Drosophila Gr28bD product is a non-specific cation channel that can be used as a novel thermogenetic tool.Scientific reports · 2018Article
- A biphasic locomotor response to acute unsignaled high temperature exposure in Drosophila.PloS one · 2018Article
8 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 1 institution in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Most attempts to localize physical correlates of memory in the central nervous system (CNS) rely on ablation techniques. This approach has the limitation of defining just one of an unknown number of structures necessary for memory formation. We have used the Drosophila rutabaga type I Ca(2+)/CaM-dependent adenylyl cyclase (AC) gene to determine in which CNS region AC expression is sufficient for memory formation. Using pan-neural and restricted CNS expression with the GAL4 binary transcription activation system, we have rescued the memory defect of the rutabaga mutant in a fast robust spatial learning paradigm. The ventral ganglion, antennal lobes, and median bundle are likely the CNS structures sufficient for rutabaga AC- dependent spatial learning.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.