ArticleThe Journal of neuroscience : the official journal of the Society for Neuroscience2000
Peripheral odor coding in the rat and frog: quality and intensity specification.
Article in The Journal of neuroscience : the official journal of the Society for Neuroscience, 2000. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 53 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
53 citing papers in PubMed.
- Evidence that interglomerular inhibition generates non-monotonic concentration-response relationships in mitral/tufted glomeruli in the mouse olfactory bulb.The Journal of physiology · 2026Article
- Odour learning concentration influences concentration range of conditioned response in newborn rabbits.Scientific reports · 2025Article
- Recalibrating Olfactory Neuroscience to the Range of Naturally Occurring Odor Concentrations.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2025Review
- Ex Vivo Multisite Electro-olfactogram Recordings in Rabbit Neonates.Methods in molecular biology (Clifton, N.J.) · 2025Article
- The primacy model and the structure of olfactory space.PLoS computational biology · 2024Article
- Depolarization block in olfactory sensory neurons expands the dimensionality of odor encoding.Science advances · 2022Article
- Biological constraints on configural odour mixture perception.The Journal of experimental biology · 2022Article
- Resolving different presynaptic activity patterns within single olfactory glomeruli of Xenopus laevis larvae.Scientific reports · 2021Article
- Article
- Odor-evoked inhibition of olfactory sensory neurons drives olfactory perception in Drosophila.Nature communications · 2017Article
- Simultaneous Loss of NCKX4 and CNG Channel Desensitization Impairs Olfactory Sensitivity.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2017Article
- The Ca2+-activated Cl- channel TMEM16B regulates action potential firing and axonal targeting in olfactory sensory neurons.The Journal of general physiology · 2016Article
- Coding of odor stimulus features among secondary olfactory structures.Journal of neurophysiology · 2015Article
- Characterizing olfactory binary mixture interactions in Fischer 344 rats using behavioral reaction times.Chemical senses · 2015Article
- Role of intraglomerular circuits in shaping temporally structured responses to naturalistic inhalation-driven sensory input to the olfactory bulb.Journal of neurophysiology · 2015Article
- A model for non-monotonic intensity coding.Royal Society open science · 2015Article
- Bulbar microcircuit model predicts connectivity and roles of interneurons in odor coding.PloS one · 2015Article
- From molecule to mind: an integrative perspective on odor intensity.Trends in neurosciences · 2014Review
- The perception of odor objects in everyday life: a review on the processing of odor mixtures.Frontiers in psychology · 2014Review
- Mechanisms underlying odorant-induced and spontaneous calcium signals in olfactory receptor neurons of spiny lobsters, Panulirus argus.Journal of comparative physiology. A, Neuroethology, sensory, neural, and behavioral physiology · 2014Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
In mammals, two recent studies have shown recently that one odor molecule can be recognized by several molecular olfactory receptors (ORs), and a single OR can recognize multiple odor molecules. In addition, one olfactory receptor neuron (ORN) may respond to different stimuli chosen as representative of distinct odor qualities. The aim of the present study was to analyze quality and intensity coding abilities of rat single ORNs, comparing them with previous extensive data gathered in the frog to get insight into the generality of olfactory coding mechanisms over vertebrates. Response properties of 90 rat ORNs to different odors or to one odor at different concentrations were analyzed. In the rat and the frog, odor quality appears to be specified through the identity of activated ORNs. However, rat ORNs have higher response thresholds. This lower sensitivity may be interpreted as an increase in selectivity of rat ORNs for low or medium odor intensities. In these conditions, the lower proportion of activated ORNs could be counterbalanced by their number, as well as by their higher glomerular convergence ratio in the olfactory bulb. From amphibians to mammals, the olfactory system appears to use universal mechanisms based on a combinatorial-coding mode that may allow quasi-infinite possibilities of adaptation to various olfactory environments.
Indexed as
Identifiers
10704512PMC6772510What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.