ArticleMediators of inflammation1999
Estimation of SLE activity based on the serum level of chosen cytokines and superoxide radical generation.
Article in Mediators of inflammation, 1999. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
13 citing papers in PubMed.
- Clinical associations of IL-10 and IL-37 in systemic lupus erythematosus.Scientific reports · 2016Trial
- Serum levels of APRIL, BAFF, and IL-10 in systemic lupus erythematosus have limited utility as biomarkers for disease activity or flare prediction.Clinical rheumatology · 2026Article
- IL-10 in Systemic Lupus Erythematosus: Balancing Immunoregulation and Autoimmunity.International journal of molecular sciences · 2025Article
- Genetic polymorphisms of glutathione S-transferases and cytochrome P450 enzymes as susceptibility factors to systemic lupus erythematosus in southern Brazilian patients.Molecular biology reports · 2014Article
- Role of interleukin-10 and interleukin-10 receptor in systemic lupus erythematosus.Clinical rheumatology · 2013Review
- Monocytes from Irf5-/- mice have an intrinsic defect in their response to pristane-induced lupus.Journal of immunology (Baltimore, Md. : 1950) · 2012Article
- Superoxide release in juvenile systemic lupus erythematosus.Rheumatology international · 2012Article
- Oxidative stress promotes hypertension and albuminuria during the autoimmune disease systemic lupus erythematosus.Hypertension (Dallas, Tex. : 1979) · 2012Article
- Tumor necrosis factor-alpha antagonist etanercept decreases blood pressure and protects the kidney in a mouse model of systemic lupus erythematosus.Hypertension (Dallas, Tex. : 1979) · 2010Article
- Cytokine-induced monocyte characteristics in SLE.Journal of biomedicine & biotechnology · 2010Article
- The pathophysiology of hypertension in systemic lupus erythematosus.American journal of physiology. Regulatory, integrative and comparative physiology · 2009Review
- Safety and efficacy of infliximab in a patient with active WHO class IV lupus nephritis.Clinical rheumatology · 2007Article
- Raised levels of interleukin 6 in systemic lupus erythematosus correlate with anaemia.Annals of the rheumatic diseases · 2005Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
We estimated the serum levels of IL-6, TNF-alpha and IL-10, and generation of superoxide radicals, as well as their mutual dependence, in 63 SLE patients at various stages of disease activity. Our results indicate a statistically significant increase of the serum levels studied, and an increase of superoxide anion generation by granulocytes, in correlation with SLE activity. These results indicate that oxygen metabolism and the examined cytokines play an important role in pathogenesis of SLE. The assessment of these parameters can be useful in the estimation of disease activity.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.