ArticleClinical and diagnostic laboratory immunology2000
Clustering of clinical strains of Helicobacter pylori analyzed by two-dimensional gel electrophoresis.
Article in Clinical and diagnostic laboratory immunology, 2000. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
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Who cites it
4 citing papers in PubMed.
- Differential proteomics of Helicobacter pylori associated with autoimmune atrophic gastritis.Molecular medicine (Cambridge, Mass.) · 2014Article
- Comparative proteome analysis of Helicobacter pylori clinical strains by two-dimensional gel electrophoresis.Journal of Zhejiang University. Science. B · 2011Article
- Comparative proteomic analysis of Lactobacillus plantarum for the identification of key proteins in bile tolerance.BMC microbiology · 2011Article
- Proteomic comparison of the cytosolic proteins of three Bifidobacterium longum human isolates and B. longum NCC2705.BMC microbiology · 2010Article
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4 authors.
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Abstract
Strain variations of Helicobacter pylori have been tested by numerous methods and compared among different patient groups. The aim of this study was to investigate whether H. pylori expresses disease-specific proteins that can be detected by two-dimensional polyacrylamide gel electrophoresis (2-D PAGE). H. pylori strains isolated from duodenal ulcer, gastric cancer, and gastritis patients were analyzed. Extensive variation in spot patterns was observed between the strains, but a dendrogram analysis revealed that some strains within each disease group clustered together. Eight proteins were sequenced and found in the H. pylori genome sequence. 2-D PAGE is a useful method for studies of protein expression and for highlighting the extensive strain variation that H. pylori exhibits.
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