ArticleClinical and diagnostic laboratory immunology2000
Characterization of a predominant immunogenic outer membrane protein of Riemerella anatipestifer.
Article in Clinical and diagnostic laboratory immunology, 2000. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers.
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Who cites it
31 citing papers in PubMed, 84 citations in OpenAlex.
- Adaptive evolution resulted in three subtypes of theJournal of bacteriology · 2026Article
- A Comprehensive Visual Detection Strategy: Versatile LAMP Assay with Phenol Red and Lateral Flow Dipstick for On-Site Detection ofMicroorganisms · 2026Article
- Research Progress in the Development of Vaccines AgainstMicroorganisms · 2025Review
- PorV factor of the type IX secretion system and PosF porin act as adhesins in Riemerella anatipestifer infection.Veterinary research · 2025Article
- Immune-iron homeostasis deciphers resistance divergence toFrontiers in microbiology · 2025Article
- Sifting through the core-genome to identify putative cross-protective antigens against Riemerella anatipestifer.Applied microbiology and biotechnology · 2023Article
- Article
- Riemerella anatipestifer AS87_RS02955 Acts as a Virulence Factor and Displays Endonuclease Activity.Applied and environmental microbiology · 2022Article
- Identification and Pathogenicity Analysis of the Pathogen Causing Spotted Spleen in Muscovy Duck.Frontiers in veterinary science · 2022Article
- PaR1 secreted by the type IX secretion system is a protective antigen ofFrontiers in microbiology · 2022Article
- Engineered DNase-inactive Cpf1 variants to improve targeting scope for base editing inSynthetic and systems biotechnology · 2021Article
- XRE-Type Regulator BioX Acts as a Negative Transcriptional Factor of Biotin Metabolism in Riemerella anatipestifer.Journal of bacteriology · 2021Article
- A Riemerella anatipestifer Metallophosphoesterase That Displays Phosphatase Activity and Is Associated with Virulence.Applied and environmental microbiology · 2021Article
- Development of a colloidal gold immunochromatographic strip for rapid detection of Riemerella anatipestifer in ducks.Poultry science · 2020Article
- Anti-inflammatory activity of diindolylmethane alleviates Riemerella anatipestifer infection in ducks.PloS one · 2020Article
- Evaluation of Long-term Antibody Response and Cross-serotype Reaction in Ducks Immunised with RecombinantJournal of veterinary research · 2019Article
- The drug tolerant persisters of Riemerella anatipestifer can be eradicated by a combination of two or three antibiotics.BMC microbiology · 2018Article
- Identifying the Genes Responsible for Iron-Limited Condition inBioMed research international · 2017Article
- Article
- Investigation of TbfA in Riemerella anatipestifer using plasmid-based methods for gene over-expression and knockdown.Scientific reports · 2016Article
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Authors and funding
7 authors at 3 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The ompA gene, encoding the 42-kDa major antigenic outer membrane protein OmpA of Riemerella anatipestifer, the etiololgical agent of septicemia anserum exsudativa, was cloned and expressed in Escherichia coli. Recombinant OmpA displayed a molecular mass similar to that predicted from the nucleotide sequence of the ompA gene but lower than that observed in total cell lysates of R. anatipestifer. The ompA gene showed a conserved C-terminal region comprising the OmpA-like domain and a variable N-terminal region. This structure is similar to those of the analogous outer membrane proteins of several gram-negative bacteria. However, OmpA of R. anatipestifer contains six EF-hand calcium-binding domains and two PEST regions, which distinguish it from other outer membrane proteins. The occurrence of these motifs in OmpA suggests a possible role in virulence for this protein. The ompA gene is present in the R. anatipestifer type strain and in all serotype reference strains. However, it exhibits some minor genetic heterogeneity among different serotypes, which seems not to affect the strong antigenic characteristics of the protein. OmpA is a conserved and strong antigenic determinant of R. anatipestifer and hence is suggested to be a valuable protein for the serodetection of R. anatipestifer infections, independent of their serotype.
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