Evidence map›Paper›PMID 10698727›Full record

ReviewEnvironmental health perspectives2000

Cyanobacterial toxins: removal during drinking water treatment, and human risk assessment.

B C Hitzfeld, S J Höger, D R Dietrich

Open access · diamondAbstract readReview
In one paragraph

Review in Environmental health perspectives, 2000. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 64 papers.

0numbers the graph read from it
0cells of the map it votes in
64citing papers in PubMed
8.4field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

64 citing papers in PubMed, 435 citations in OpenAlex.

  1. Freshwater Harmful Algal Blooms (HABS) Public Health Message Efficacy Evaluation.Journal of contemporary water research & education · 2026
    Article
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  5. Review
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  14. Wildfires in the western United States are mobilizing PMEnvironmental science. Processes & impacts · 2023
    Article
  15. A review of plant-based coagulants for turbidity and cyanobacteria blooms removal.Environmental science and pollution research international · 2022
    Review
  16. Article
  17. Article
  18. Innovative method of utilising hydrogen peroxide for source water management of cyanobacteria.Environmental science and pollution research international · 2022
    Article
  19. Spirulina platensis protects against microcystin-LR-induced toxicity in rats.Environmental science and pollution research international · 2022
    Article
  20. Article

4 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

B C HitzfeldEnvironmental Toxicology, University of Konstanz, Konstanz, Germany. bettina.hitzfeld@uni-konstanz.de
S J Höger
D R Dietrich
University of Konstanz · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cyanobacteria (blue-green algae) produce toxins that may present a hazard for drinking water safety. These toxins (microcystins, nodularins, saxitoxins, anatoxin-a, anatoxin-a(s), cylindrospermopsin) are structurally diverse and their effects range from liver damage, including liver cancer, to neurotoxicity. The occurrence of cyanobacteria and their toxins in water bodies used for the production of drinking water poses a technical challenge for water utility managers. With respect to their removal in water treatment procedures, of the more than 60 microcystin congeners, microcystin-LR (L, L-leucine; R, L-arginine) is the best studied cyanobacterial toxin, whereas information for the other toxins is largely lacking. In response to the growing concern about nonlethal acute and chronic effects of microcystins, the World Health Organization has recently set a new provisional guideline value for microcystin-LR of 1.0 microg/L drinking water. This will lead to further efforts by water suppliers to develop effective treatment procedures to remove these toxins. Of the water treatment procedures discussed in this review, chlorination, possibly micro-/ultrafiltration, but especially ozonation are the most effective in destroying cyanobacteria and in removing microcystins. However, these treatments may not be sufficient during bloom situations or when a high organic load is present, and toxin levels should therefore be monitored during the water treatment process. In order to perform an adequate human risk assessment of microcystin exposure via drinking water, the issue of water treatment byproducts will have to be addressed in the future.

Indexed as

AnimalsCyanobacteriaHumansMarine ToxinsRisk AssessmentWater SupplyMarine Toxins

Identifiers

PMID10698727
PMCPMC1637783
OpenAlexW2110069146

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.