ArticleBiophysical journal2000
Growing an actin gel on spherical surfaces.
Article in Biophysical journal, 2000. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 54 papers.
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Who cites it
54 citing papers in PubMed.
- On the Assembly of Actin Polymerization-Powered Motors.Macromolecular rapid communications · 2026Article
- Reconstituted systems for studying the architecture and dynamics of actin networks.The Biochemical journal · 2025Review
- Myosin-I synergizes with Arp2/3 complex to enhance the pushing forces of branched actin networks.Science advances · 2024Article
- On the generation of force required for actin-based motility.Scientific reports · 2024Article
- Article
- Myosin-I Synergizes with Arp2/3 Complex to Enhance Pushing Forces of Branched Actin Networks.bioRxiv : the preprint server for biology · 2024Article
- Machine learning-enabled constrained multi-objective design of architected materials.Nature communications · 2023Article
- The Effect of Magnetic Field Gradient and Gadolinium-Based MRI Contrast Agent Dotarem on Mouse Macrophages.Cells · 2022Article
- Actin modulates shape and mechanics of tubular membranes.Science advances · 2020Article
- Mechanical stiffness of reconstituted actin patches correlates tightly with endocytosis efficiency.PLoS biology · 2019Article
- Kinetics of surface growth with coupled diffusion and the emergence of a universal growth path.Proceedings. Mathematical, physical, and engineering sciences · 2019Article
- Guided by curvature: shaping cells by coupling curved membrane proteins and cytoskeletal forces.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2018Review
- Magnetic Field Changes Macrophage Phenotype.Biophysical journal · 2018Article
- A new method to measure mechanics and dynamic assembly of branched actin networks.Scientific reports · 2017Article
- DNA cytoskeleton for stabilizing artificial cells.Proceedings of the National Academy of Sciences of the United States of America · 2017Article
- Bending, Pushing, and Ratcheting It Up: Memories of a Modeling Effort.Biophysical journal · 2016Article
- Toward the reconstitution of synthetic cell motility.Cell adhesion & migration · 2016Review
- How capping protein enhances actin filament growth and nucleation on biomimetic beads.Physical biology · 2015Article
- Theoretical study of actin layers attachment and separation.The European physical journal. E, Soft matter · 2015Article
- Influence of substrate curvature on osteoblast orientation and extracellular matrix deposition.Journal of biological engineering · 2013Article
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Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Inspired by the motility of the bacteria Listeria monocytogenes, we have experimentally studied the growth of an actin gel around spherical beads grafted with ActA, a protein known to be the promoter of bacteria movement. On ActA-grafted beads F-actin is formed in a spherical manner, whereas on the bacteria a "comet-like" tail of F-actin is produced. We show experimentally that the stationary thickness of the gel depends on the radius of the beads. Moreover, the actin gel is not formed if the ActA surface density is too low. To interpret our results, we propose a theoretical model to explain how the mechanical stress (due to spherical geometry) limits the growth of the actin gel. Our model also takes into account treadmilling of actin. We deduce from our work that the force exerted by the actin gel on the bacteria is of the order of 10 pN. Finally, we estimate from our theoretical model possible conditions for developing actin comet tails.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.