ArticleBiophysical journal2000
Rigidity of triskelion arms and clathrin nets.
Article in Biophysical journal, 2000. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
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Who cites it
15 citing papers in PubMed, 39 citations in OpenAlex.
- De novo endocytic clathrin coats develop curvature at early stages of their formation.Developmental cell · 2021Article
- Label-retention expansion microscopy.The Journal of cell biology · 2021Article
- The AP2 adaptor enhances clathrin coat stiffness.The FEBS journal · 2019Article
- Mechanotransduction in tumor progression: The dark side of the force.The Journal of cell biology · 2018Review
- Utilizing clathrin triskelions as carriers for spatially controlled multi-protein display.Biomaterials · 2016Article
- Membrane fluctuations destabilize clathrin protein lattice order.Biophysical journal · 2014Article
- Micellization model for the polymerization of clathrin baskets.The Journal of chemical physics · 2013Article
- Unraveling protein-protein interactions in clathrin assemblies via atomic force spectroscopy.Methods (San Diego, Calif.) · 2013Article
- Fishing for clathrin-coated pit nucleators.Nature cell biology · 2012Article
- A TACC3/ch-TOG/clathrin complex stabilises kinetochore fibres by inter-microtubule bridging.The EMBO journal · 2011Article
- AFM visualization of clathrin triskelia under fluid and in air.FEBS letters · 2010Article
- Clathrin triskelia show evidence of molecular flexibility.Biophysical journal · 2008Article
- Conformation of a clathrin triskelion in solution.Biochemistry · 2006Article
- Measuring the elasticity of clathrin-coated vesicles via atomic force microscopy.Biophysical journal · 2006Article
- Clathrin self-assembly involves coordinated weak interactions favorable for cellular regulation.The EMBO journal · 2003Article
Corrections and comments
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Authors and funding
2 authors at 1 institution in 1 country.
Funding
Abstract
Statistical analysis is applied to a set of electron micrographic images (Kocsis, E., B. L. Trus, C. J. Steer, M. E. Bisher, and A. C. Steven. 1991. J. Struct. Biol. 107:6-14), from which quantitative measures are obtained to support the notion that the three arms of a triskelion have statistically identical properties and exhibit independent structural fluctuations. Additionally, a study of local contour fluctuations, which indicates that the elastic properties of a triskelion arm are approximately constant over the entire arm length, is used along with a small deformation statistical mechanics theory to derive an effective, average flexural rigidity for the arms. This result is used to estimate the bending energy necessary to deform a clathrin patch, and comparison is made with the deformation energy of an equivalent area of non-clathrin-coated membrane. We estimate that the rigidity of the clathrin lattice is at least comparable to that of a typical membrane. Hence, the natural curvature of a clathrin cage can stabilize, and perhaps propel, the formation of intracellular coated vesicles.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.