Trial reportBMJ (Clinical research ed.)2000
Randomised trial of monitoring, feedback, and management of care by telephone to improve treatment of depression in primary care.
Trial report in BMJ (Clinical research ed.), 2000. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05633186 (Sustainable Upscaling of Depression Prevention, Finding the Optimal Balance Between Investment and Benefit), which is not on this map. Cited by 146 papers, 16 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Sustainable Upscaling of Depression Prevention, Finding the Optimal Balance Between Investment and Benefit (SPRINT)
Who cites it
146 citing papers in PubMed, 16 syntheses or guidelines pooled it.
- The effectiveness of enhanced evidence-based care for depressive disorders: a meta-analysis of randomized controlled trials.Translational psychiatry · 2021Pooled it
- Elusive search for effective provider interventions: a systematic review of provider interventions to increase adherence to evidence-based treatment for depression.Implementation science : IS · 2018Pooled it
- Interventions to reduce wait times for primary care appointments: a systematic review.BMC health services research · 2017Pooled it
- Automated telephone communication systems for preventive healthcare and management of long-term conditions.The Cochrane database of systematic reviews · 2016Pooled it
- Routine use of patient reported outcome measures (PROMs) for improving treatment of common mental health disorders in adults.The Cochrane database of systematic reviews · 2016Pooled it
- Collaborative chronic care models for mental health conditions: cumulative meta-analysis and metaregression to guide future research and implementation.Medical care · 2013Pooled it
- Collaborative care for depression and anxiety problems.The Cochrane database of systematic reviews · 2012Pooled it
- Audit and feedback: effects on professional practice and healthcare outcomes.The Cochrane database of systematic reviews · 2012Pooled it
- Do productivity costs matter?: the impact of including productivity costs on the incremental costs of interventions targeted at depressive disorders.PharmacoEconomics · 2011Pooled it
- Effect of outpatient pharmacists' non-dispensing roles on patient outcomes and prescribing patterns.The Cochrane database of systematic reviews · 2010Pooled it
- On-site mental health workers delivering psychological therapy and psychosocial interventions to patients in primary care: effects on the professional practice of primary care providers.The Cochrane database of systematic reviews · 2009Pooled it
- Psychotherapy mediated by remote communication technologies: a meta-analytic review.BMC psychiatry · 2008Pooled it
- A systematic review of complex system interventions designed to increase recovery from depression in primary care.BMC health services research · 2006Pooled it
- Primary care mental health workers: models of working and evidence of effectiveness.The British journal of general practice : the journal of the Royal College of General Practitioners · 2002Pooled it
- Interventions used in disease management programmes for patients with chronic illness-which ones work? Meta-analysis of published reports.BMJ (Clinical research ed.) · 2002Pooled it
- Computer-generated patient education materials: do they affect professional practice? A systematic review.Journal of the American Medical Informatics Association : JAMIAPooled it
- Collaborative care intervention for risky opioid use among primary care patients: The STOP randomized clinical trial.Addiction (Abingdon, England) · 2026Trial
- The care manager meeting the patients' unique needs using the care manager model-A qualitative study of experienced care managers.BMC family practice · 2021Trial
- A randomized trial of Volunteer Recovery Support for Adolescents (VRSA) following residential treatment discharge.Journal of substance abuse treatment · 2019Trial
- A Randomized Trial of Off-Site Collaborative Care for Depression in Chronic Hepatitis C Virus.Health services research · 2018Trial
86 more citing papers are in PubMed but not listed here.
Corrections and comments
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Authors and funding
4 authors.
Funding
Abstract
objectiveTo test the effectiveness of two programmes to improve the treatment of acute depression in primary care.
designRandomised trial.
settingPrimary care clinics in Seattle. PATIENTS: 613 patients starting antidepressant treatment.
interventionPatients were randomly assigned to continued usual care or one of two interventions: feedback only and feedback plus care management. Feedback only comprised feedback and algorithm based recommendations to doctors on the basis of data from computerised records of pharmacy and visits. Feedback plus care management included systematic follow up by telephone, sophisticated treatment recommendations, and practice support by a care manager.
main outcome measuresBlinded interviews by telephone 3 and 6 months after the initial prescription included a 20 item depression scale from the Hopkins symptom checklist and the structured clinical interview for the current DSM-IV depression module. Visits, antidepressant prescriptions, and overall use of health care were assessed from computerised records.
resultsCompared with usual care, feedback only had no significant effect on treatment received or patient outcomes. Patients receiving feedback plus care management had a higher probability of both receiving at least moderate doses of antidepressants (odds ratio 1.99, 95% confidence interval 1.23 to 3.22) and a 50% improvement in depression scores on the symptom checklist (2.22, 1.31 to 3.75), lower mean depression scores on the symptom checklist at follow up, and a lower probability of major depression at follow up (0.46, 0.24 to 0.86). The incremental cost of feedback plus care management was about $80 ( pound50) per patient.
conclusionsMonitoring and feedback to doctors yielded no significant benefits for patients in primary care starting antidepressant treatment. A programme of systematic follow up and care management by telephone, however, significantly improved outcomes at modest cost.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.