ArticleArchives of disease in childhood2000
Infant feeding and adult glucose tolerance, lipid profile, blood pressure, and obesity.
Article in Archives of disease in childhood, 2000. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03900663 (Nutritional Status and Body Composition of Children in Relation to Mode of Delivery and Feeding in the First 2 Years of Life), which is not on this map. Cited by 63 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Nutritional Status and Body Composition of Children in Relation to Mode of Delivery and Feeding in the First 2 Years of Life
Who cites it
63 citing papers in PubMed, 2 syntheses or guidelines pooled it, 329 citations in OpenAlex.
- Workplace programmes for supporting breast-feeding: a systematic review and meta-analysis.Public health nutrition · 2021Pooled it
- Breastfeeding and Type 2 Diabetes: Systematic Review and Meta-Analysis.Current diabetes reports · 2019Pooled it
- Breastfeeding, genetic susceptibility, and type 2 diabetes in offspring in later life.Obesity (Silver Spring, Md.) · 2025Article
- Human Breast Milk Exosomes: Affecting Factors, Their Possible Health Outcomes, and Future Directions in Dietetics.Nutrients · 2024Review
- Role of breastfeeding in disease prevention.Microbial biotechnology · 2024Review
- Maternal smoking, nutritional factors at different life stage, and the risk of incident type 2 diabetes: a prospective study of the UK Biobank.BMC medicine · 2024Article
- Effect and Concern of Breastfeeding in Infants.Juntendo Iji zasshi = Juntendo medical journal · 2024Review
- Significance of lipids, lipoproteins, and apolipoproteins during the first 14-16 months of life.European heart journal · 2023Article
- Dynamic stability of cholesterol and desmosterol in human milk from four Asian countries.Food science and biotechnology · 2022Article
- Heart Mitochondrial Metabolic Flexibility and Redox Status Are Improved by Donkey and Human Milk Intake.Antioxidants (Basel, Switzerland) · 2021Article
- Personalized Nutrition Approach in Pregnancy and Early Life to Tackle Childhood and Adult Non-Communicable Diseases.Life (Basel, Switzerland) · 2021Review
- Human Milk Exosomal MicroRNA: Associations with Maternal Overweight/Obesity and Infant Body Composition at 1 Month of Life.Nutrients · 2021Article
- Efficacy and Safety of Combined Extracts ofJournal of clinical medicine · 2020Article
- The Perinatal Condition Around Birth and Cardiovascular Risk Factors in the Japanese General Population: The Suita Study.Journal of atherosclerosis and thrombosis · 2020Article
- Early life feeding and current dietary patterns are associated with biomarkers of glucose and lipid metabolism in young women from the Nutritionist's Health Study.European journal of clinical nutrition · 2020Article
- Effectiveness of a new approach for exclusive breastfeeding counselling on breastfeeding prevalence, infant growth velocity and postpartum weight loss in overweight or obese women: protocol for a randomized controlled trial.International breastfeeding journal · 2020Article
- Breastfeeding duration in infancy and adult risks of type 2 diabetes in a high-income country.Maternal & child nutrition · 2019Article
- Breastfeeding and cardiometabolic markers at age 12: a population-based birth cohort study.International journal of obesity (2005) · 2019Article
- The Lipid and Glyceride Profiles of Infant Formula Differ by Manufacturer, Region and Date Sold.Nutrients · 2019Article
- Family Factors Associated with Selected Childhood Nutrition Aspects in Central Poland.International journal of environmental research and public health · 2019Article
3 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 1 institution in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundIt is generally accepted that breast feeding has a beneficial effect on the health of infants and young children. Recently, a few studies have shown that the method of infant feeding is also associated with cardiovascular disease and its risk factors in adult life.
aimsTo examine the association between the method of infant feeding in the first weeks after birth and glucose tolerance, plasma lipid profile, blood pressure, and body mass in adults aged 48-53 years.
methodsSubjects born at term between 1 November 1943 and 28 February 1947 in the Wilhelmina Gasthuis in Amsterdam around the time of a severe period of famine (late November 1944 to early May 1945). For 625 subjects, information was available about infant feeding at the time of discharge from hospital (on average 10.4 days after birth), and at least one blood sample after an overnight fast.
resultsSubjects who were bottle fed had a higher mean 120 minute plasma glucose concentration after a standard oral glucose tolerance test than those who were exclusively breast fed. They also had a higher plasma low density lipoprotein (LDL) cholesterol concentration, a lower high density lipoprotein (HDL) cholesterol concentration, and a higher LDL/HDL ratio. Systolic blood pressure and body mass index were not affected by the method of infant feeding.
conclusionsExclusive breast feeding seems to have a protective effect against some risk factors for cardiovascular disease in later life.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.