ArticleThe Journal of neuroscience : the official journal of the Society for Neuroscience2000
Calcium transients in the rhabdomeres of dark- and light-adapted fly photoreceptor cells.
Article in The Journal of neuroscience : the official journal of the Society for Neuroscience, 2000. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
What it found
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Who cites it
18 citing papers in PubMed, 59 citations in OpenAlex.
- Retinal TRP channels: Cell-type-specific regulators of retinal homeostasis and multimodal integration.Progress in retinal and eye research · 2023Review
- Dietary restriction and the transcription factor clock delay eye aging to extend lifespan in Drosophila Melanogaster.Nature communications · 2022Article
- The Role of Membrane Lipids in Light-Activation ofBiomolecules · 2022Review
- Transduction and Adaptation Mechanisms in the Cilium or Microvilli of Photoreceptors and Olfactory Receptors From Insects to Humans.Frontiers in cellular neuroscience · 2021Review
- Rapid Release of CaThe Journal of neuroscience : the official journal of the Society for Neuroscience · 2020Article
- Calcium signalling in Drosophila photoreceptors measured with GCaMP6f.Cell calcium · 2017Article
- Fractional Ca(2+) currents through TRP and TRPL channels in Drosophila photoreceptors.Biophysical journal · 2013Article
- Compartmentalization and Ca2+ buffering are essential for prevention of light-induced retinal degeneration.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2012Article
- Phototransduction and the evolution of photoreceptors.Current biology : CB · 2010Review
- Phototransduction motifs and variations.Cell · 2009Review
- Article
- Systems analysis of the single photon response in invertebrate photoreceptors.Proceedings of the National Academy of Sciences of the United States of America · 2008Article
- Visual coding in locust photoreceptors.PloS one · 2008Article
- Phototransduction and retinal degeneration in Drosophila.Pflugers Archiv : European journal of physiology · 2007Review
- Light dependence of oxygen consumption by blowfly eyes recorded with a magnetic diver balance.Journal of comparative physiology. A, Neuroethology, sensory, neural, and behavioral physiology · 2005Article
- Regulation by voltage and adenine nucleotides of a Ca2+-activated cation channel from hamster vomeronasal sensory neurons.The Journal of physiology · 2003Article
- Light adaptation in Drosophila photoreceptors: I. Response dynamics and signaling efficiency at 25 degrees C.The Journal of general physiology · 2001Article
- Calcium imaging demonstrates colocalization of calcium influx and extrusion in fly photoreceptors.Proceedings of the National Academy of Sciences of the United States of America · 2000Article
Corrections and comments
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Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The light response of fly photoreceptor cells is modulated by changes in free Ca(2+) concentration. Fly phototransduction and most processes regulating it take place in or very close to the rhabdomere. We therefore measured the kinetics and the absolute values of the free Ca(2+) concentration in the rhabdomere of fly photoreceptor cells in vivo by making use of the natural optics of the fly's eye. We show that Ca(2+) flowing into the rhabdomere after light stimulation of dark-adapted cells causes fast Ca(2+) transients that reach peak values higher than 200 microM in <20 msec. Approximately 500 msec later, the free Ca(2+) concentration has declined again to approximately 20 microM. The duration of the Ca(2+) transients becomes still shorter, and their size reduced, when the photoreceptor cell is light-adapted. This reduction in duration and size of the Ca(2+) transients is graded with the intensity of the adapting light. The kinetics and absolute values of the free calcium concentration found to occur in the rhabdomere are suitable to mediate the fast feedback signals known to act on the fly phototransduction cascade.
Indexed as
Identifiers
10684872PMC6772907W2101630905What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.