Evidence map›Paper›PMID 10684308›Full record

ArticleJournal of virology2000

Superantigen expression is driven by both mouse mammary tumor virus long terminal repeat-associated promoters in transgenic mice.

B Salmons, T Miethke, S Wintersperger, M Müller, G Brem, W H Günzburg

Open access · bronzeAbstract read
In one paragraph

Article in Journal of virology, 2000. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact, top 88% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 6 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 2 countries.

B SalmonsBavarian Nordic, D-82152 Martinsried, Germany.
T Miethke
S Wintersperger
M Müller
G Brem
W H Günzburg
Bavarian Nordic (Germany) · DEInstitute of Bioinformatics and Systems Biology · DEInstitute of Medical Microbiology and Hygiene · DEUniversity of Veterinary Medicine Vienna · AT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In addition to the usual retroviral promoter, the mouse mammary tumor virus (MMTV) long terminal repeat carries a second promoter located in the U3 region. Here we show that both of these promoters are independently able to give rise to superantigen activity in transgenic mice. The ability of multiple MMTV promoters to drive superantigen expression underscores its importance in the virus life cycle.

Indexed as

Gene Expression Regulation, ViralPromoter Regions, GeneticTerminal Repeat SequencesAnimalsAntigens, ViralMammary Tumor Virus, MouseMiceMice, Inbred C57BLMice, TransgenicSuperantigensAntigens, ViralSuperantigens

Identifiers

PMID10684308
PMCPMC111782
OpenAlexW2099619063

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.