ArticleInfection and immunity2000
Eimeria tenella infection induces local gamma interferon production and intestinal lymphocyte subpopulation changes.
Article in Infection and immunity, 2000. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
36 citing papers in PubMed, 118 citations in OpenAlex.
- Protective immunity against Eimeria tenella infection in chickens following oral immunization with Bacillus subtilis expressing Eimeria tenella 3-1E protein.Parasitology research · 2015Trial
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- Exploring the interplay betweenThe veterinary quarterly · 2025Review
- Impact of partially defatted black soldier fly larvae meal on coccidia-infected chickens: effects on growth performance, intestinal health, and cecal short-chain fatty acid concentrations.Journal of animal science and biotechnology · 2025Article
- Article
- Insights of early feeding regime supplemented with glutamine and various levels of omega-3 in broiler chickens: growth performance, muscle building, antioxidant capacity, intestinal barriers health and defense against mixedThe veterinary quarterly · 2024Article
- Growth performance and immune response of broilers during activeAnimal nutrition (Zhongguo xu mu shou yi xue hui) · 2024Article
- Endoparasite survey in Amazonian manatees (International journal for parasitology. Parasites and wildlife · 2024Article
- Eimeria: Navigating complex intestinal ecosystems.PLoS pathogens · 2024Review
- Effects of Dietary Inclusion of a Proprietary Combination ofAnimals : an open access journal from MDPI · 2024Article
- Prophylactic and Therapeutic Efficacy of Ultrasonicated Rosmarinus officinalis Ethanolic Extract and its Chitosan-Loaded Nanoparticles Against Eimeria tenella Infected Broiler Chickens.Acta parasitologica · 2024Article
- Anticoccidial activity of Aloe Vera Leafs' aqueous extract and vaccination against Eimeria tenella: pathological study in broilers.Veterinary research communications · 2024Article
- Effects of fermentedFrontiers in cellular and infection microbiology · 2024Article
- Evaluation of a dacitic (rhyolitic) tuff breccia use on performance, inflammatory, and antioxidant responses in broilers mildly challenged with Eimeria spp.Poultry science · 2023Article
- Effect of Immunomodulation in Turkeys Infected with Haemorrhagic Enteritis Virus on the Percentage of CD4Journal of veterinary research · 2022Article
- Dietary supplementation of sulfur amino acids improves intestinal immunity toAnimal nutrition (Zhongguo xu mu shou yi xue hui) · 2022Article
- Effect of organic acids on growth performance, intestinal morphology, and immunity of broiler chickens with and without coccidial challenge.AMB Express · 2021Article
- Expression of Chicken NK-Lysin and Its Role in Chicken Coccidiosis Induced by Eimeria necatrix.The Korean journal of parasitology · 2021Article
- Immunomodulatory Effects of Dietary Phosphorus and Calcium in Two Strains of Laying Hens.Animals : an open access journal from MDPI · 2021Article
- Kinetics of the Cellular and Transcriptomic Response toFrontiers in immunology · 2021Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The role of intestinal lymphocytes and gamma interferon (IFN-gamma) production in protective immunity to Eimeria tenella infection was evaluated in two inbred strains of chickens (SC and TK) that display different patterns of susceptibility to coccidiosis. Oral inoculation of either strain with E. tenella led to parasite invasion of the intestinal cecum and cecal tonsils. Greater fecal oocyst shedding was seen in TK chickens. Flow cytometric analyses of cecal tonsil lymphocytes demonstrated greater numbers of CD4(+) and T-cell receptor gammadelta-positive (TCR1(+)) cells in SC chickens and elevated numbers of CD8(+) and TCR2(+) cells in TK chickens following primary infection. IFN-gamma mRNA expression was significantly increased in cecal tonsil and intraepithelial lymphocytes at days 6 and 8, respectively, after primary infection in SC compared to TK chickens. While no differences were noted between cecal tonsil lymphocytes of the two strains following secondary infection, TK chickens showed elevated IFN-gamma transcript levels in intestinal intraepithelial lymphocytes at this time. Selective depletion of CD4(+), but not CD8(+), cecal tonsil lymphocytes in SC chickens resulted in a reduced IFN-gamma mRNA expression, indicating that CD4(+) cells are the primary source of this cytokine. Collectively, these results indicate that local lymphocyte responses and production of IFN-gamma are influenced by host genetic factors.
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