ReviewThe EMBO journal2000
Macromolecular mimicry.
Review in The EMBO journal, 2000. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
17 citing papers in PubMed.
- Protein Fold Usages in Ribosomes: Another Glance to the Past.International journal of molecular sciences · 2024Article
- Rationally designed inhibitors of the Musashi protein-RNA interaction by hotspot mimicry.Research square · 2023Article
- Rationally designed inhibitors of the Musashi protein-RNA interaction by hotspot mimicry.bioRxiv : the preprint server for biology · 2023Article
- Placeholder factors in ribosome biogenesis: please, pave my way.Microbial cell (Graz, Austria) · 2017Review
- The conserved GTPase HflX is a ribosome splitting factor that binds to the E-site of the bacterial ribosome.Nucleic acids research · 2016Article
- Molecular evolution of protein-RNA mimicry as a mechanism for translational control.Nucleic acids research · 2014Article
- Structural insights into protein-only RNase P complexed with tRNA.Nature communications · 2013Article
- Molecular dynamics of ribosomal elongation factors G and Tu.European biophysics journal : EBJ · 2011Article
- Elongation in translation as a dynamic interaction among the ribosome, tRNA, and elongation factors EF-G and EF-Tu.Quarterly reviews of biophysics · 2009Review
- Yeast ribosomal protein L10 helps coordinate tRNA movement through the large subunit.Nucleic acids research · 2008Article
- HEXIM1 forms a transcriptionally abortive complex with glucocorticoid receptor without involving 7SK RNA and positive transcription elongation factor b.Proceedings of the National Academy of Sciences of the United States of America · 2005Article
- The structure of a rigorously conserved RNA element within the SARS virus genome.PLoS biology · 2005Article
- Cryo-EM reveals an active role for aminoacyl-tRNA in the accommodation process.The EMBO journal · 2002Article
- Autoimmune epitopes in messenger RNA.RNA (New York, N.Y.) · 2002Article
- Substrate promiscuity of an aminoglycoside antibiotic resistance enzyme via target mimicry.The EMBO journal · 2002Article
- The ribosomal binding and peptidyl-tRNA hydrolysis functions of Escherichia coli release factor 2 are linked through residue 246.RNA (New York, N.Y.) · 2000Article
- Crystal structure combined with genetic analysis of the Thermus thermophilus ribosome recycling factor shows that a flexible hinge may act as a functional switch.RNA (New York, N.Y.) · 2000Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Some proteins have been shown to mimic the overall shape and structure of nucleic acids. For some of the proteins involved in translating the genetic information into proteins on the ribosome particle, there are indications that such observations of macromolecular mimicry even extend to similarity in interaction with and function on the ribosome. A small number of structural results obtained outside the protein biosynthesis machinery could indicate that the concept of macromolecular mimicry between proteins and nucleic acids is more general. The implications for the function and evolution of protein biosynthesis are discussed.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.