Evidence map›Paper›PMID 10675211›Full record

ArticleJournal of neurology, neurosurgery, and psychiatry2000

Corticobasal ganglionic degeneration and/or frontotemporal dementia? A report of two overlap cases and review of literature.

P S Mathuranath, J H Xuereb, T Bak, J R Hodges

Open access · bronzeAbstract readCase Reports
In one paragraph

Article in Journal of neurology, neurosurgery, and psychiatry, 2000. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
4.4field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 107 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Review
  6. Imaging-pathologic correlation in corticobasal degeneration.AJNR. American journal of neuroradiology · 2009
    Article
  7. Rapidly progressive dementia.Neurologic clinics · 2007
    Review
  8. Visuospatial functions in atypical parkinsonian syndromes.Journal of neurology, neurosurgery, and psychiatry · 2006
    Article
  9. The clinical assessment of the patient with early dementia.Journal of neurology, neurosurgery, and psychiatry · 2005
    Review
  10. Article
  11. Presenile dementia syndromes: an update on taxonomy and diagnosis.Journal of neurology, neurosurgery, and psychiatry · 2002
    Review
  12. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

P S MathuranathUniversity of Cambridge Neurology Unit, Addenbrooke's Hospital, Cambridge, UK.
J H Xuereb
T Bak
J R Hodges
Addenbrooke's Hospital · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveAccording to the existing viewpoint, Corticobasal degeneration (CBD) is thought of as a predominantly extrapyramidal motor disorder that is distinct and unrelated to frontotemporal dementia (FTD), the most common form of non-Alzheimer dementias. A lack of understanding of the aetiopathogenesis, and poor correlation between the pathology and the clinical syndromes, has resulted in a disparity in the classification of cases of non-Alzheimer dementias. This report intends to highlight the overlap between FTD and CBD in the light of the evolution of these terms, and to discuss the implications of these findings on the nosology of CBD and the classification of non-Alzheimer dementias. METHODS AND

resultsTwo cases who presented with cognitive dysfunction, which, on comprehensive neuropsychological testing warranted an antemortem diagnosis of FTD are reported. A detailed necropsy study of their brains, however, favoured a pathological diagnosis of CBD. The literature on the overlap between CBD and FTD is also reviewed.

conclusionsFirstly, evidence is emerging to suggest that the clear distinction drawn between FTD and CBD by the existing viewpoint, needs revision. Secondly, until such time that a comprehensive classification of non-Alzheimer dementias is evolved, it may be better to distinguish between the clinical and pathological levels of description and to classify cases, in vivo, on the basis of the clinical phenotype.

Indexed as

AgedBasal Ganglia DiseasesCerebral CortexDementiaFemaleFrontal LobeHumansMiddle AgedNeuropsychological TestsTemporal Lobe

Identifiers

PMID10675211
PMCPMC1736839
OpenAlexW2144773945

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.