ArticleThe Journal of physiology2000
Heterodimeric amino acid transporters: expression of heavy but not light chains of CD98 correlates with induction of amino acid transport systems in human placental trophoblast.
Article in The Journal of physiology, 2000. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
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Who cites it
11 citing papers in PubMed, 33 citations in OpenAlex.
- Regulation of placental amino acid transport in health and disease.Acta physiologica (Oxford, England) · 2024Review
- Homocysteine transport by systems L, A and y+L across the microvillous plasma membrane of human placenta.The Journal of physiology · 2009Article
- Genomic regulation of intestinal amino acid transporters by aldosterone.Molecular and cellular biochemistry · 2008Article
- The membrane-spanning domain of CD98 heavy chain promotes alpha(v)beta3 integrin signals in human extravillous trophoblasts.Molecular endocrinology (Baltimore, Md.) · 2008Article
- Manipulation of CD98 expression affects both trophoblast cell fusion and amino acid transport activity during syncytialization of human placental BeWo cells.The Journal of physiology · 2003Article
- Transport and metabolism of amino acids in placenta.Endocrine · 2002Review
- Activation of system L heterodimeric amino acid exchangers by intracellular substrates.The EMBO journal · 2002Article
- Role of the System L permease LAT1 in amino acid and iodothyronine transport in placenta.The Biochemical journal · 2001Article
- Characterisation of L-tryptophan transporters in human placenta: a comparison of brush border and basal membrane vesicles.The Journal of physiology · 2001Article
- Further characterization of 5-HT1A receptors in the goldfish retina: role of cyclic AMP in the regulation of the in vitro outgrowth of retinal explants.Neurochemical research · 2001Article
- The role of L-tryptophan transport in L-tryptophan degradation by indoleamine 2,3-dioxygenase in human placental explants.The Journal of physiology · 2001Article
Corrections and comments
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Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
1. Activity of amino acid transport and relative abundance of mRNAs encoding related transporters have been studied in parallel either before or following in vitro culture of explants of human placental chorionic villi. 2. Amino acid transport activities through systems L (1.9-fold), y+L (2.6-fold) and y+ (3.2-fold) were markedly enhanced following culture for 48 h. 3. Relative mRNA abundance (determined by reverse transcription-polymerase chain reaction) for the heavy chain of CD98 surface antigen and for the cationic amino acid transporter-1 were similarly stimulated (2.8-fold and 2.6-fold, respectively). In contrast, none of the mRNA levels for light chains of CD98 (system L-amino acid transporter-1, system L-amino acid transporter-2, system y+L-amino acid transporter-1 and system y+L-amino acid transporter-2) studied nor for the cationic amino acid transporter-2B were altered.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.