Evidence map›Paper›PMID 10671469›Full record

ArticleJournal of bacteriology2000

Requirement for homologous recombination functions for expression of the mutA mistranslator tRNA-induced mutator phenotype in Escherichia coli.

L Ren, A A Al Mamun, M Z Humayun

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of bacteriology, 2000. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.9field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 11 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

L RenDepartment of Microbiology and Molecular Genetics, University of Medicine and Dentistry of New Jersey-New Jersey Medical School, Newark, New Jersey 07103-2714, USA.
A A Al Mamun
M Z Humayun
Rutgers New Jersey Medical SchoolRutgers, The State University of New Jersey · US

Funding

MECHANISMS OF MISTRANSLATION MEDIATED MUTATOR RESPONSER01GM058253 · NIGMS · UNIV OF MED/DENT OF NJ-NJ MEDICAL SCHOOL · PI HUMAYUN, M. ZAFRI · 1998 to 2009
$1.6M
MECHANISMS OF INDUCIBLE ERROR PRONE DNA REPLICATIONR01CA073026 · NCI · UNIV OF MED/DENT OF NJ-NJ MEDICAL SCHOOL · PI HUMAYUN, M. ZAFRI · 1997 to 2004
$1.3M
NCI NIH HHS R01 CA073026NCI NIH HHS R01 CA73026NIGMS NIH HHS R01 GM058253NIGMS NIH HHS R01 GM58253
6 · The paper itself

Abstract

Expression of the Escherichia coli mutA mutator phenotype requires recA, recB, recC, ruvA, and ruvC gene, but not recD, recF, recO, or recR genes. Thus, the recBCD-dependent homologous recombination system is a component of the signal pathway that activates an error-prone DNA polymerase in mutA cells.

Indexed as

DNA HelicasesEscherichia coli ProteinsBacterial ProteinsDNA-Binding ProteinsEndodeoxyribonucleasesEscherichia coliExodeoxyribonucleasesExodeoxyribonuclease VGene Expression Regulation, BacterialGenes, BacterialMutationPhenotypeRec A RecombinasesRecombination, GeneticRNA, TransferSignal TransductionBacterial ProteinsDNA-Binding ProteinsDNA HelicasesEndodeoxyribonucleasesEscherichia coli ProteinsExodeoxyribonucleasesExodeoxyribonuclease Vexodeoxyribonuclease V, E coliHolliday junction DNA helicase, E coliRec A RecombinasesRNA, TransferruvC protein, E coli

Identifiers

PMID10671469
PMCPMC94434
OpenAlexW2108159813

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.