Evidence map›Paper›PMID 10666282›Full record

ArticleJournal of virology2000

The c-myc locus is a common integration site in type B retrovirus-induced T-cell lymphomas.

L Rajan, D Broussard, M Lozano, C G Lee, C A Kozak, J P Dudley

Open access · greenAbstract read
In one paragraph

Article in Journal of virology, 2000. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
0.9field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 25 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

L RajanSection of Molecular Genetics and Microbiology and Institute for Cellular and Molecular Biology, The University of Texas at Austin, Austin, Texas 78705, USA.
D Broussard
M Lozano
C G Lee
C A Kozak
J P Dudley
The University of Texas at Austin · USNational Institute of Allergy and Infectious Diseases · USNational Institutes of Health · US

Funding

GENETIC CONTROL OF RESISTANCE TO FRIEND VIRUS IN WILD MOUSE POPULATIONSZ01AI000300 · NIAID · NIAID EXTRAMURAL ACTIVITIES · PI KOZAK, CHRISTINE · 1985 to 2008
$1.3M
TRANSCRIPTIONAL REGULATION AND TUMORIGENESIS BY MMTVR01CA034780 · NCI · UNIVERSITY OF TEXAS AUSTIN · PI DUDLEY, JAQUELIN PAGE · 1985 to 2002
$821k
NCI NIH HHS CA34780
6 · The paper itself

Abstract

Type B leukemogenic virus (TBLV) induces rapidly appearing T-cell leukemias. TBLV insertions near the c-myc gene were detectable in 2 of 30 tumors tested, whereas 80% of the tumors showed c-myc overexpression. TBLV insertions on chromosome 15 (including a newly identified locus, Pad7) may cause c-myc overexpression by cis-acting effects at a distance.

Indexed as

AnimalsBetaretrovirusChromosome MappingGenes, mycLymphoma, T-CellMiceMice, Inbred BALB CMice, Inbred C57BLVirus Integration

Identifiers

PMID10666282
PMCPMC111733
OpenAlexW2168956559

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.