ArticleArchives of internal medicine1976
Partial deletion of long arm of chromosome 17: a specific abnormality in acute promyelocytic leukemia?
Article in Archives of internal medicine, 1976. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
12 citing papers in PubMed.
- The Expendables: Overlooked Medications with Anti-Cancer Properties.Current oncology reports · 2025Review
- History of Developing Acute Promyelocytic Leukemia Treatment and Role of Promyelocytic Leukemia Bodies.Cancers · 2024Review
- Does the pursuit of scientific excellence serve or hamper translational medical research: an historical perspective from hematological malignancies.Blood cancer journal · 2022Review
- History of Acute Promyelocytic Leukemia.Clinical hematology international · 2021Review
- Article
- Acute Promyelocytic Leukemia: A History over 60 Years-From the Most Malignant to the most Curable Form of Acute Leukemia.Oncology and therapy · 2019Review
- ATRA-induced upregulation of Beclin 1 prolongs the life span of differentiated acute promyelocytic leukemia cells.Autophagy · 2011Article
- All trans retinoic acid in acute promyelocytic leukemia.Oncogene · 2001Review
- Acute promyelocytic leukemia.The Western journal of medicine · 1987Article
- Incidence of the 15q+;17q- chromosome translocation in acute promyelocytic leukaemia (APL).British journal of cancer · 1985Article
- Chromosomal assignment of the human homologues of feline sarcoma virus and avian myeloblastosis virus onc genes.Proceedings of the National Academy of Sciences of the United States of America · 1982Article
- 15/17 translocation in acute promyelocytic leukaemia.Human genetics · 1978Article
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Two patients with acute promyelocytic leukemia had an identical chromosomal abnormality detected by fluoresecence banding. In each case, the clinical course was rapidly fatal, and was characterized by a lack of response to chemotherapy with cytarabine and thioguanine, and was complicated by disseminated intravascular coagulation. Bone marrow cells from each patient contained 46 chromosomes; in each instance, however, one chromosome 17 had a deletion of almost one half of the proximal portion of the long arm [del(17)(q11q21 or 22)].
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Registered trials
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