ArticleJournal of molecular neuroscience : MN1999
Characterization of the chicken transitin gene reveals a strong relationship to the nestin intermediate filament class.
Article in Journal of molecular neuroscience : MN, 1999. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
3 citing papers in PubMed, 8 citations in OpenAlex.
- Review
- Aggrecan is expressed by embryonic brain glia and regulates astrocyte development.Developmental biology · 2008Article
- Molecular evolution of type VI intermediate filament proteins.BMC evolutionary biology · 2007Article
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Authors and funding
3 authors at 1 institution in 2 countries.
Funding
Abstract
Our laboratory previously reported that transitin is a radial glial intermediate filament protein sharing the basic structural features common to all intermediate filament (IF) proteins. It contains an alpha-helical core domain flanked by a short nonhelical head and a long COOH-terminal tail. The core sequence of transitin shows the greatest similarity to Xenopus tanabin and to rat and human nestin. We also reported that transitin has multiple splice variants derived from the deletion or inclusion of a leucine-zipper heptad repeat domain in the COOH-terminal tail. In the present study, we provide new evidence to support the classification of nestin and transitin in the same group of IF proteins based on the number and position of its introns. In addition, we suggest that the different isoforms of transitin are produced by a splicing mechanism that recognizes consensus 5' and 3' splice sites contained within the coding sequence of the leucine-zipper heptad repeat domain.
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