ArticleJapanese journal of cancer research : Gann1999
Clonal analysis of adenosquamous carcinoma of the lung.
Article in Japanese journal of cancer research : Gann, 1999. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
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Who cites it
17 citing papers in PubMed.
- A case of coexistent poorly differentiated adenosquamous carcinoma (glassy cell carcinoma), usual-type adenocarcinoma, and squamous cell carcinoma in situ of the cervix.Medical molecular morphology · 2023Article
- Epithelial cell plasticity: breaking boundaries and changing landscapes.EMBO reports · 2021Review
- Adenocarcinomatous-predominant subtype associated with a better prognosis in adenosquamous lung carcinoma.BMC cancer · 2020Article
- Pathological transition as the arising mechanism for drug resistance in lung cancer.Cancer communications (London, England) · 2019Review
- Adenosquamous carcinoma of the lung.OncoTargets and therapy · 2018Review
- Research progress of the clinicopathologic features of lung adenosquamous carcinoma.OncoTargets and therapy · 2018Review
- PD-L1 expression in lung adenosquamous carcinomas compared with the more common variants of non-small cell lung cancer.Scientific reports · 2017Article
- Screening for major driver oncogene alterations in adenosquamous lung carcinoma using PCR coupled with next-generation and Sanger sequencing methods.Scientific reports · 2016Article
- Article
- Clinicopathological characteristics and prognosis of patients with adenosquamous lung carcinoma.Journal of Huazhong University of Science and Technology. Medical sciences = Hua zhong ke ji da xue xue bao. Yi xue Ying De wen ban = Huazhong keji daxue xuebao. Yixue Yingdewen ban · 2015Article
- Clinicopathological features and surgical outcomes of adenosquamous carcinoma of the pancreas: a retrospective analysis of patients with resectable stage tumors.Surgery today · 2015Article
- Clinical significance of PIK3CA and survivin in primary adenosquamous lung carcinoma.Medical oncology (Northwood, London, England) · 2014Article
- Adenosquamous cell lung cancer successfully treated with gefitinib: A case report.Molecular and clinical oncology · 2014Article
- Prognostic impact of serum CYFRA 21-1 in patients with advanced lung adenocarcinoma: a retrospective study.BMC cancer · 2013Article
- Article
- Clinicopathological characteristics of resected adenosquamous cell carcinoma of the lung: risk of coexistent double cancer.Journal of cardiothoracic surgery · 2010Article
- Article
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5 authors.
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Abstract
Adenosquamous carcinoma of the lung is a subset of pulmonary carcinomas, and comprises less than 4% of lung carcinomas. Its histogenesis remains unclear. The clonality of adenosquamous carcinoma from four female patients was analyzed to determine whether the clonality between the squamous cell and adenocarcinomatous components coincides. Each lesion was precisely microdissected from methanol-fixed sections. Adjacent normal lung tissue was collected as a normal control. DNA was extracted for clonal analysis based on an X-chromosome-linked polymorphic marker, the human androgen receptor gene (HUMARA). HUMARA was found to be amplified with or without previous digestion by the methylation-sensitive restriction endonuclease HpaII. All four cases were informative. Squamous cell and adenocarcinomatous components showed identical monoclonal patterns in all four patients. In one case, only the squamous cell carcinomatous component showed loss of heterozygosity of the HUMARA locus. The results suggest that the squamous cell and adenocarcinomatous components originate from the same cell.
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