ArticleEnvironmental health perspectives2000
Strategies for assessing the implications of malformed frogs for environmental health.
Article in Environmental health perspectives, 2000. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
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Who cites it
12 citing papers in PubMed, 90 citations in OpenAlex.
- Congenital Anomalies in American Crocodile (Veterinary sciences · 2024Article
- Tissue-Specific Distribution of Legacy and Emerging Organophosphorus Flame Retardants and Plasticizers in Frogs.Toxics · 2021Article
- Habitat quality affects the incidence of morphological abnormalities in the endangered salamander Ambystoma ordinarium.PloS one · 2017Article
- Assessment of heavy metals and metalloids in tissues of two frog species: Rana tigrina and Euphlyctis cyanophlyctis from industrial city Sialkot, Pakistan.Environmental science and pollution research international · 2015Article
- Terrestrial pesticide exposure of amphibians: an underestimated cause of global decline?Scientific reports · 2013Article
- Localized hotspots drive continental geography of abnormal amphibians on U.S. wildlife refuges.PloS one · 2013Article
- Morphological abnormalities in frogs from a rice-growing region in NSW, Australia, with investigations into pesticide exposure.Environmental monitoring and assessment · 2011Article
- Acclimation to low level exposure of copper in Bufo arenarum embryos: linkage of effects to tissue residues.International journal of environmental research and public health · 2007Article
- Proximity to pollution sources and risk of amphibian limb malformation.Environmental health perspectives · 2005Article
- Assessing the toxicity and teratogenicity of pond water in north-central Minnesota to amphibians.Environmental science and pollution research international · 2004Article
- Synergism between trematode infection and pesticide exposure: a link to amphibian limb deformities in nature?Proceedings of the National Academy of Sciences of the United States of America · 2002Article
- Mitogen-activated protein kinase activation by oxidative and bacterial stress in an amphibian cell culture model.Environmental health perspectives · 2002Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
19 authors at 6 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The recent increase in the incidence of deformities among natural frog populations has raised concern about the state of the environment and the possible impact of unidentified causative agents on the health of wildlife and human populations. An open workshop on Strategies for Assessing the Implications of Malformed Frogs for Environmental Health was convened on 4-5 December 1997 at the National Institute of Environmental Health Sciences in Research Triangle Park, North Carolina. The purpose of the workshop was to share information among a multidisciplinary group with scientific interest and responsibility for human and environmental health at the federal and state level. Discussions highlighted possible causes and recent findings directly related to frog deformities and provided insight into problems and strategies applicable to continuing investigation in several areas. Possible causes of the deformities were evaluated in terms of diagnostics performed on field amphibians, biologic mechanisms that can lead to the types of malformations observed, and parallel laboratory and field studies. Hydrogeochemistry must be more integrated into environmental toxicology because of the pivotal role of the aquatic environment and the importance of fates and transport relative to any potential exposure. There is no indication of whether there may be a human health factor associated with the deformities. However, the possibility that causal agents may be waterborne indicates a need to identify the relevant factors and establish the relationship between environmental and human health in terms of hazard assessment.
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Registered trials
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