Evidence map›Paper›PMID 10611382›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America1999

BAS1: A gene regulating brassinosteroid levels and light responsiveness in Arabidopsis.

M M Neff, S M Nguyen, E J Malancharuvil, S Fujioka, T Noguchi, H Seto, M Tsubuki, T Honda, S Takatsuto, S Yoshida and 1 more

Open access · greenAbstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 1999. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 141 papers.

0numbers the graph read from it
0cells of the map it votes in
141citing papers in PubMed
29.4field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

141 citing papers in PubMed, 380 citations in OpenAlex.

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  20. Article

81 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 5 institutions in 2 countries.

M M NeffPlant Biology Laboratory, The Salk Institute for Biological Studies, 10010 North Torrey Pines Road, La Jolla, CA 92037, USA.
S M Nguyen
E J Malancharuvil
S Fujioka
T Noguchi
H Seto
M Tsubuki
T Honda
S Takatsuto
S Yoshida
J Chory
Joetsu University of Education · JPRIKEN · JPHoward Hughes Medical Institute · USHoshi University · JPSalk Institute for Biological Studies · US

Funding

INITIAL EVENTS IN PHOTORECEPTOR SIGNALINGR01GM052413 · NIGMS · SALK INSTITUTE FOR BIOLOGICAL STUDIES · PI CHORY, JOANNE · 1995 to 2016
$5.4M
CLONING AN EXTRAGENIC SUPPRESSOR OF PHYB-ARABIDOPSISF32GM017577 · NIGMS · SALK INSTITUTE FOR BIOLOGICAL STUDIES · PI NEFF, MICHAEL M · 1996 to 1998
–
NIGMS NIH HHS F32 GM017577NIGMS NIH HHS GM17577NIGMS NIH HHS R01 GM052413NIGMS NIH HHS R01GM52413
6 · The paper itself

Abstract

The Arabidopsis bas1-D mutation suppresses the long hypocotyl phenotype caused by mutations in the photoreceptor phytochrome B (phyB). The adult phenotype of bas1-D phyB-4 double mutants mimics that of brassinosteroid biosynthetic and response mutants. bas1-D phyB-4 has reduced levels of brassinosteroids and accumulates 26-hydroxybrassinolide in feeding experiments. The basis for the mutant phenotype is the enhanced expression of a cytochrome P450 (CYP72B1). bas1-D suppresses a phyB-null allele, but not a phyA-null mutation, and partially suppresses a cryptochrome-null mutation. Seedlings with reduced BAS1 expression are hyperresponsive to brassinosteroids in a light-dependent manner and display reduced sensitivity to light under a variety of conditions. Thus, BAS1 represents one of the control points between multiple photoreceptor systems and brassinosteroid signal transduction.

Indexed as

Drosophila ProteinsEye ProteinsGenes, PlantPhotoreceptor CellsPhotoreceptor Cells, InvertebrateTranscription FactorsArabidopsisArabidopsis ProteinsBrassinosteroidsCholestanolsCryptochromesDose-Response Relationship, DrugDose-Response Relationship, RadiationFlavoproteinsLightMutationArabidopsis ProteinsBAS1 protein, ArabidopsisbrassinolideBrassinosteroidsCholestanolsCRY1 protein, Arabidopsiscry protein, DrosophilaCryptochromesDrosophila ProteinsEye ProteinsFlavoproteinsPeroxidasesPeroxiredoxinsPHYB protein, ArabidopsisPhytochromePhytochrome BPhytosterolsReceptors, G-Protein-CoupledSteroids, HeterocyclicTranscription Factors

Identifiers

PMID10611382
PMCPMC24817
OpenAlexW2045567689

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.