ArticleJournal of clinical pathology1999
Clinicopathological features of serrated adenoma of the colorectum: comparison with traditional adenoma.
Article in Journal of clinical pathology, 1999. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
12 citing papers in PubMed, 1 synthesis or guideline pooled it, 51 citations in OpenAlex.
- Evidence-based clinical practice guidelines for management of colorectal polyps.Journal of gastroenterology · 2015Guideline
- The Differential Diagnosis of Colorectal Polyps Using Colon Capsule Endoscopy.Internal medicine (Tokyo, Japan) · 2021Article
- Evidence-based clinical practice guidelines for management of colorectal polyps.Journal of gastroenterology · 2021Review
- The clinical impact of serrated colorectal polyps.Clinical epidemiology · 2017Review
- Expression of gastric pyloric mucin, MUC6, in colorectal serrated polyps.Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc · 2010Article
- Clinico-pathological aspects of colorectal serrated adenomas.World journal of gastroenterology · 2006Article
- Different apoptotic activity and p21(WAF1/CIP1), but not p27(Kip1), expression in serrated adenomas as compared with traditional adenomas and hyperplastic polyps of the colorectum.Journal of cancer research and clinical oncology · 2003Article
- No major tumorigenic role for beta-catenin in serrated as opposed to conventional colorectal adenomas.British journal of cancer · 2003Article
- Article
- Three-dimensional reconstruction and fractal geometric analysis of serrated adenoma.Japanese journal of cancer research : Gann · 2002Article
- Serrated adenoma in familial adenomatous polyposis: relation to germline APC gene mutation.Gut · 2002Article
- Fas ligand upregulation is an early event in colonic carcinogenesis.Journal of clinical pathology · 2001Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
aimSerrated adenoma is a recently described category of colorectal adenoma. The aim of this study was to determine whether serrated adenomas have clinicopathological findings distinct from "traditional" adenoma.
methodsColonoscopy records for 1995-1998 were reviewed, and all traditional adenomas and serrated adenomas identified. Tumour site and endoscopic configuration were compared between the two types of adenoma. In polypectomised lesions, size and grade of dysplasia were compared between the two groups.
resultsThere were 3305 traditional adenomas and 43 serrated adenomas. Serrated adenomas were more often found in the rectosigmoid colon than the traditional adenomas (67.5% v 41.2%, p = 0.0008). Polypectomy was more often done for serrated adenomas (27 of 43 lesions, 62.8%) than for traditional adenomas (626 of 3305 lesions, 18.9%, p < 0.0001). Size (mean (SD) maximum dimension, 12 (6) mm v 13 (3) mm) and incidence of high grade dysplasia (14.8% v 13.6%) in endoscopically removed specimens were not different between the two types.
conclusionsThe therapeutic judgement applied to the management of traditional adenoma seems to be appropriate for serrated adenoma.
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