ADD-1 provides major new insight into the mechanism of insulin action.

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

Who cites it

8 citing papers in PubMed.

1. Biochemical and cellular properties of insulin receptor signalling.Nature reviews. Molecular cell biology · 2018
   Review
2. POSSIBLE REGULATION OF LDL-RECEPTOR BY NARINGENIN IN HEPG2 HEPATOMA CELL LINE.African journal of traditional, complementary, and alternative medicines : AJTCAM · 2017
   Article
3. Ring finger protein20 regulates hepatic lipid metabolism through protein kinase A-dependent sterol regulatory element binding protein1c degradation.Hepatology (Baltimore, Md.) · 2014
   Article
4. Dual functions of Insig proteins in cholesterol homeostasis.Lipids in health and disease · 2012
   Review
5. High-carbohydrate diets affect the size and composition of plasma lipoproteins in hamsters (Mesocricetus auratus).Comparative medicine · 2008
   Article
6. Maintaining cholesterol homeostasis: sterol regulatory element-binding proteins.World journal of gastroenterology · 2004
   Review
7. Metabolic complications associated with HIV protease inhibitor therapy.Drugs · 2003
   Review
8. Nutrient control of gene expression in Drosophila: microarray analysis of starvation and sugar-dependent response.The EMBO journal · 2002
   Article

Corrections and comments

• Comment on
  Sterol regulatory element binding protein-1c is a major mediator of insulin action on the hepatic expression of glucokinase and lipogenesis-related genes.1999
• Comment on
  Insulin selectively increases SREBP-1c mRNA in the livers of rats with streptozotocin-induced diabetes.1999

Authors and funding

2 authors.

Funding

No grant is acknowledged in the PubMed record.

Abstract

PubMed holds no abstract for this paper.

Indexed as