ArticleMolecular biology of the cell1999
Circulation of the plasma membrane in Dictyostelium.
Article in Molecular biology of the cell, 1999. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
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Who cites it
32 citing papers in PubMed.
- Article
- Making cups and rings: the 'stalled-wave' model for macropinocytosis.Biochemical Society transactions · 2024Review
- Wound Repair of the Cell Membrane: Lessons fromCells · 2024Review
- Procedures to Measure Dictyostelium Phagocytosis and Macropinocytosis.Methods in molecular biology (Clifton, N.J.) · 2024Article
- Molecular Shape Solution for Mesoscopic Remodeling of Cellular Membranes.Annual review of biophysics · 2022Review
- Article
- On the existence of endocytosis driven by membrane phase separations.Biochimica et biophysica acta. Biomembranes · 2020Review
- High-throughput Measurement of Dictyostelium discoideum Macropinocytosis by Flow Cytometry.Journal of visualized experiments : JoVE · 2018Article
- The physiological regulation of macropinocytosis duringJournal of cell science · 2018Article
- Turnover and flow of the cell membrane for cell migration.Scientific reports · 2017Article
- WASH drives early recycling from macropinosomes and phagosomes to maintain surface phagocytic receptors.Proceedings of the National Academy of Sciences of the United States of America · 2016Article
- Article
- Article
- Article
- Two distinct functions for PI3-kinases in macropinocytosis.Journal of cell science · 2013Article
- Phosphorylation of actin-related protein 2 (Arp2) is required for normal development and cAMP chemotaxis in Dictyostelium.The Journal of biological chemistry · 2013Article
- How do amoebae swim and crawl?PloS one · 2013Article
- Cell motility: the integrating role of the plasma membrane.European biophysics journal : EBJ · 2011Review
- Endocytic and recycling endosomes modulate cell shape changes and tissue behaviour during morphogenesis in Drosophila.PloS one · 2011Article
- The exocytic gene secA is required for Dictyostelium cell motility and osmoregulation.Journal of cell science · 2010Article
Corrections and comments
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Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
We have developed a fluorimetric assay with the use of the dye FM1-43 to determine the rate at which Dictyostelium amoebae endocytose their surface membrane. Our results show that they do so about once each 4-10 min. A clathrin null mutant takes its surface up only approximately 30% more slowly, showing that this membrane uptake cannot be caused by clathrin-coated vesicles. Surprisingly, Ax2 and its parent, NC4, which differ in their rates of fluid-phase internalization by approximately 60-fold, take up their surfaces at the same rates. These results show that, in axenic cells, the uptake of fluid and of surface area are separate processes. The large activity of this new endocytic cycle in both Ax2 and NC4 amoebae appears capable of delivering sufficient new surface area to advance the cells' fronts during migration.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.