ArticleGenetics1999
The Mla (powdery mildew) resistance cluster is associated with three NBS-LRR gene families and suppressed recombination within a 240-kb DNA interval on chromosome 5S (1HS) of barley.
Article in Genetics, 1999. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 93 papers.
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Who cites it
93 citing papers in PubMed.
- Characterization and mapping of a rust resistance locus in the common bean landrace G19833.G3 (Bethesda, Md.) · 2025Article
- Identification of Powdery Mildew Resistance-Related Genes in Butternut Squash (International journal of molecular sciences · 2024Article
- Genome-wide association mapping for seedling and adult resistance to powdery mildew in barley.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2024Article
- Barley MLA3 recognizes the host-specificity effector Pwl2 from Magnaporthe oryzae.The Plant cell · 2024Article
- The NLRomes of Zea mays NAM founder lines and Zea luxurians display presence-absence variation, integrated domain diversity, and mobility.Molecular plant pathology · 2023Article
- Germplasm Screening Using DNA Markers and Genome-Wide Association Study for the Identification of Powdery Mildew Resistance Loci in Tomato.International journal of molecular sciences · 2022Article
- The barley leaf rust resistance gene Rph3 encodes a predicted membrane protein and is induced upon infection by avirulent pathotypes of Puccinia hordei.Nature communications · 2022Article
- Discovery of Resistance Genes in Rye by Targeted Long-Read Sequencing and Association Genetics.Cells · 2022Article
- The barley immune receptor Mla recognizes multiple pathogens and contributes to host range dynamics.Nature communications · 2021Article
- Plant NLR diversity: the known unknowns of pan-NLRomes.The Plant cell · 2021Review
- Diploid chromosome-scale assembly of the Muscadinia rotundifolia genome supports chromosome fusion and disease resistance gene expansion during Vitis and Muscadinia divergence.G3 (Bethesda, Md.) · 2021Article
- You Had Me at "MAGIC"!: Four Barley MAGIC Populations Reveal Novel Resistance QTL for Powdery Mildew.Genes · 2020Article
- Molecular dissection of resistance gene cluster and candidate gene identification of PlScientific reports · 2019Article
- Diversification of the downy mildew resistance gene pool by introgression of a new gene, PlTAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2019Article
- High Resolution Mapping ofFrontiers in plant science · 2019Article
- Fine mapping of powdery mildew resistance gene Pm4e in bread wheat (Triticum aestivum L.).Planta · 2018Article
- Differentially Expressed Genes Associated with the Cabbage Yellow-Green-Leaf Mutant in theInternational journal of molecular sciences · 2018Article
- The gene conferring susceptibility to spot blotch caused by Cochliobolus sativus is located at the Mla locus in barley cultivar Bowman.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2018Article
- Regulation and Evolution of NLR Genes: A Close Interconnection for Plant Immunity.International journal of molecular sciences · 2018Review
- Interchromosomal Transfer of Immune Regulation During Infection of Barley with the Powdery Mildew Pathogen.G3 (Bethesda, Md.) · 2017Article
33 more citing papers are in PubMed but not listed here.
Corrections and comments
- Erratum issued
Authors and funding
9 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Powdery mildew of barley, caused by Erysiphe graminis f. sp. hordei, is a model system for investigating the mechanism of gene-for-gene interaction between large-genome cereals and obligate-fungal pathogens. A large number of loci that confer resistance to this disease are located on the short arm of chromosome 5(1H). The Mla resistance-gene cluster is positioned near the telomeric end of this chromosome arm. AFLP-, RAPD-, and RFLP-derived markers were used to saturate the Mla region in a high-resolution recombinant population segregating for the (Mla6 + Mla14) and (Mla13 + Ml-Ru3) resistance specificities. These tightly linked genetic markers were used to identify and develop a physical contig of YAC and BAC clones spanning the Mla cluster. Three distinct NBS-LRR resistance-gene homologue (RGH) families were revealed via computational analysis of low-pass and BAC-end sequence data derived from Mla-spanning clones. Genetic and physical mapping delimited the Mla-associated, NBS-LRR gene families to a 240-kb interval. Recombination within the RGH families was at least 10-fold less frequent than between markers directly adjacent to the Mla cluster.
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