Evidence map›Paper›PMID 10577986›Full record

ReviewAnnals of the rheumatic diseases1999

Immunomodulation by thalidomide and thalidomide analogues.

L G Corral, G Kaplan

Registry-linked trialAbstract readReview
In one paragraph

Review in Annals of the rheumatic diseases, 1999. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02446236 (Phase Ib Dose Finding Study of Bruton's Tyrosine Kinase), which is not on this map. Cited by 52 papers.

0numbers the graph read from it
0cells of the map it votes in
52citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02446236 phase1active not recruitingnot on this mapstarted 2015, after this paper: background citation

Phase Ib Dose Finding Study of Bruton's Tyrosine Kinase (BTK) Inhibitor, Ibrutinib (PCI-32765) Plus Lenalidomide / Rituximab in Relapsed or Refractory Mantle Cell Lymphoma (MCL)

TypeinterventionalSponsorHackensack Meridian HealthRan2015 to 2026Enrolled27ConditionsMantle Cell LymphomaArmsLenalidomide, Ibrutinib, Rituximab
3 · Its place in the literature

Who cites it

52 citing papers in PubMed.

  1. Trial
  2. Relationship of treatment-related cytopenias and response to lenalidomide in patients with lower-risk myelodysplastic syndromes.Journal of clinical oncology : official journal of the American Society of Clinical Oncology · 2008
    Trial
  3. Article
  4. Article
  5. Article
  6. Repurposing approved drugs for cancer therapy.British medical bulletin · 2021
    Review
  7. Hypnotic effect of thalidomide is independent of teratogenic ubiquitin/proteasome pathway.Proceedings of the National Academy of Sciences of the United States of America · 2020
    Article
  8. Review
  9. Review
  10. Review
  11. Review
  12. Article
  13. Article
  14. Article
  15. Article
  16. Host-Directed Therapies for Tuberculosis.Cold Spring Harbor perspectives in medicine · 2015
    Review
  17. Article
  18. Article
  19. Host-directed therapeutics for tuberculosis: can we harness the host?Microbiology and molecular biology reviews : MMBR · 2013
    Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

L G CorralCelgene Corporation, Warren, NJ, USA.
G Kaplan

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

HumansImmunosuppressive AgentsThalidomideTumor Necrosis Factor-alphaImmunosuppressive AgentsThalidomideTumor Necrosis Factor-alpha

Identifiers

PMID10577986
PMCPMC1766578

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.