SynthesisJournal of general internal medicine1999
The effects of information framing on the practices of physicians.
Synthesis in Journal of general internal medicine, 1999. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 45 papers, 5 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
45 citing papers in PubMed, 5 syntheses or guidelines pooled it.
- Pooled it
- A systematic review of tools for predicting severe adverse events following patient discharge from intensive care units.Critical care (London, England) · 2013Pooled it
- Using alternative statistical formats for presenting risks and risk reductions.The Cochrane database of systematic reviews · 2011Pooled it
- American society of clinical oncology clinical practice guideline update on the use of pharmacologic interventions including tamoxifen, raloxifene, and aromatase inhibition for breast cancer risk reduction.Journal of clinical oncology : official journal of the American Society of Clinical Oncology · 2009Guideline
- Describing treatment effects to patients.Journal of general internal medicine · 2003Pooled it
- Educating physicians on strong opioids by descriptive versus simulated-experience formats: a randomized controlled trial.BMC medical education · 2022Trial
- Testing feedback message framing and comparators to address prescribing of high-risk medications in nursing homes: protocol for a pragmatic, factorial, cluster-randomized trial.Implementation science : IS · 2017Trial
- Doctors and patients' susceptibility to framing bias: a randomized trial.Journal of general internal medicine · 2011Trial
- The effect of how outcomes are framed on decisions about whether to take antihypertensive medication: a randomized trial.PloS one · 2010Trial
- The effect of alternative graphical displays used to present the benefits of antibiotics for sore throat on decisions about whether to seek treatment: a randomized trial.PLoS medicine · 2009Trial
- The effect of alternative summary statistics for communicating risk reduction on decisions about taking statins: a randomized trial.PLoS medicine · 2009Trial
- How should the impact of different presentations of treatment effects on patient choice be evaluated? A pilot randomized trial.PloS one · 2008Trial
- Randomized trial evaluating the framing of cardiovascular risk and its impact on blood pressure control [ISRCTN87597585].BMC health services research · 2001Trial
- Effects of information framing on the intentions of family physicians to prescribe long-term hormone replacement therapy.Journal of general internal medicine · 1999Trial
- Warning people about the risk of AI error mitigates human acquisition of AI bias.Cognitive research: principles and implications · 2026Article
- Evaluation of adverse drug reaction formatting in drug information databases.Journal of the Medical Library Association : JMLA · 2020Article
- Article
- When evidence says no: gynaecologists' reasons for (not) recommending ineffective ovarian cancer screening.BMJ quality & safety · 2020Article
- Benefits and harms of selective oestrogen receptor modulators (SERMs) to reduce breast cancer risk: a cross-sectional study of methods to communicate risk in primary care.The British journal of general practice : the journal of the Royal College of General Practitioners · 2019Article
- Can nudge-interventions address health service overuse and underuse? Protocol for a systematic review.BMJ open · 2019Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveThe presentation format of clinical trial results, or the "frame," may influence perceptions about the worth of a treatment. The extent and consistency of that influence are unclear. We undertook a systematic review of the published literature on the effects of information framing on the practices of physicians.
designRelevant articles were retrieved using bibliographic and electronic searches. Information was extracted from each in relation to study design, frame type, parameter assessed, assessment scale, clinical setting, intervention, results, and factors modifying the frame effect. MAIN
resultsTwelve articles reported randomized trials investigating the effect of framing on doctors' opinions or intended practices. Methodological shortcomings were numerous. Seven papers investigated the effect of presenting clinical trial results in terms of relative risk reduction, or absolute risk reductions or the number needing to be treated; gain/loss (positive/negative) terms were used in four papers; verbal/numeric terms in one. In simple clinical scenarios, results expressed in relative risk reduction or gain terms were viewed most positively by doctors. Factors that reduced the impact of framing included the risk of causing harm, preexisting prejudices about treatments, the type of decision, the therapeutic yield, clinical experience, and costs. No study investigated the effect of framing on actual clinical practice.
conclusionsWhile a framing effect may exist, particularly when results are presented in terms of proportional or absolute measures of gain or loss, it appears highly susceptible to modification, and even neutralization, by other factors that influence doctors' decision making. Its effects on actual clinical practice are unknown.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.