ArticleMolecular and cellular biochemistry1999
Receptor-Ck regulates the expression of cyclin-dependent kinase inhibitors (p16; p27).
Article in Molecular and cellular biochemistry, 1999. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
5 citing papers in PubMed, 9 citations in OpenAlex.
- Lipid profile in oral submucous fibrosis.Lipids in health and disease · 2009Article
- Role of cholesterol in parasitic infections.Lipids in health and disease · 2005Review
- Receptor-Ck regulates giardia encystation process.Molecular and cellular biochemistry · 2001Article
- Molecular link between cholesterol, cytokines and atherosclerosis.Molecular and cellular biochemistry · 2001Review
- Receptor-Ck regulates membrane-bound 125 kDa protein having affinity for genomic sterol regulatory sequence.Molecular and cellular biochemistry · 2001Article
Corrections and comments
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Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The present study was addressed to understand the interrelationship between Receptor-Ck induction-activation coupling; isoprenoids (derived from mevalonate pathway) and cyclin-dependent kinase inhibitors. The results reported here unambiguously reveal that isoprenoids regulate the expression of genes coding for CDK inhibited p16 and p27. Further, Receptor-Ck dependent signalling, known to control the mevalonate pathway, had a direct effect upon the p27 gene expression. Based upon these studies coupled with our earlier findings we propose that Receptor-Ck has an important role in the regulation of cell cycle machinery.
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