ArticleGenome research1999
Identification of candidate coding region single nucleotide polymorphisms in 165 human genes using assembled expressed sequence tags.
Article in Genome research, 1999. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
29 citing papers in PubMed, 114 citations in OpenAlex.
- Article
- Association between IRS1 Gene Polymorphism and Autism Spectrum Disorder: A Pilot Case-Control Study in Korean Males.International journal of molecular sciences · 2016Article
- High quality SNPs/Indels mining and characterization in ginger from ESTs data base.Bioinformation · 2015Article
- Mining of haplotype-based expressed sequence tag single nucleotide polymorphisms in citrus.BMC genomics · 2013Article
- Development and characterisation of an expressed sequence tags (EST)-derived single nucleotide polymorphisms (SNPs) resource in rainbow trout.BMC genomics · 2012Article
- Identification, validation and high-throughput genotyping of transcribed gene SNPs in cassava.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2012Article
- SNP markers and their impact on plant breeding.International journal of plant genomics · 2012Article
- The impact of single nucleotide polymorphism in monomeric alpha-amylase inhibitor genes from wild emmer wheat, primarily from Israel and Golan.BMC evolutionary biology · 2010Article
- Mining for single nucleotide polymorphisms in pig genome sequence data.BMC genomics · 2009Article
- A SNP transferability survey within the genus Vitis.BMC plant biology · 2008Article
- A reference integrated map for cultivated grapevine (Vitis vinifera L.) from three crosses, based on 283 SSR and 501 SNP-based markers.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2008Article
- Expressed sequence tag analysis and development of gene associated markers in a near-isogenic plant system of Eragrostis curvula.Plant molecular biology · 2008Article
- Molecular evolution of dimeric alpha-amylase inhibitor genes in wild emmer wheat and its ecological association.BMC evolutionary biology · 2008Article
- Establishment of a pipeline to analyse non-synonymous SNPs in Bos taurus.BMC genomics · 2006Article
- QualitySNP: a pipeline for detecting single nucleotide polymorphisms and insertions/deletions in EST data from diploid and polyploid species.BMC bioinformatics · 2006Article
- Characterisation of single nucleotide polymorphisms in sugarcane ESTs.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2006Article
- SNPServer: a real-time SNP discovery tool.Nucleic acids research · 2005Article
- Using cDNA and genomic sequences as tools to develop SNP strategies in cassava (Manihot esculenta Crantz).TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2005Article
- A unigene catalogue of 5700 expressed genes in cassava.Plant molecular biology · 2004Article
- A transcript finishing initiative for closing gaps in the human transcriptome.Genome research · 2004Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 1 institution in 1 country.
Funding
Abstract
Using assembled expressed sequence tags (ESTs) from 50 different cDNA libraries, we have identified contigs that represent the complete coding sequences of 850 known human genes, and have scanned these for high quality sequence substitutions. We report the identification and characteristics of 201 candidate single nucleotide polymorphisms found in the coding sequences (cSNPs) of 165 of these genes. Using a conservative calculation, coding region nucleotide diversity (the average number of differences between any pair of chromosomes) was found to be 3 per 10,000 bp based on this data. This analysis reveals that assembled ESTs from multiple libraries may provide a rich source of comparative sequences to search for cSNPs in the human genome.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.