Evidence map›Paper›PMID 10567598›Full record

ArticlePostgraduate medical journal1999

Diagnostic work-up in peripheral neuropathy: an analysis of 171 cases.

D Lubec, W Müllbacher, J Finsterer, B Mamoli

Open access · bronzeAbstract read
In one paragraph

Article in Postgraduate medical journal, 1999. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
0.7field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 61 citations in OpenAlex.

  1. Clinical Cues for the Early Diagnosis of Transthyretin-Related Polyneuropathy.Journal of clinical neurology (Seoul, Korea) · 2024
    Article
  2. Article
  3. Neurosurgical Intervention for Nerve and Muscle Biopsies.Diagnostics (Basel, Switzerland) · 2024
    Review
  4. Observational
  5. CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne · 2023
    Review
  6. Diagnosis and management of patients with polyneuropathy.CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne · 2023
    Review
  7. Article
  8. Alcohol Consumption as a Causator and/or an Accelerator of Neuropathy in People With Diabetes Is Regularly Overlooked.Diabetes therapy : research, treatment and education of diabetes and related disorders · 2021
    Article
  9. Review
  10. Article
  11. Article
  12. Time to Onset of Paresthesia Among Community Members Exposed to the World Trade Center Disaster.International journal of environmental research and public health · 2019
    Article
  13. Diabetes and obesity are the main metabolic drivers of peripheral neuropathy.Annals of clinical and translational neurology · 2018
    Article
  14. Article
  15. Article
  16. Article
  17. Review
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

D LubecLudwig Boltzmann Institute for Epilepsy and Neuromuscular Disorders, Vienna, Austria.
W Müllbacher
J Finsterer
B Mamoli
Ludwig Boltzmann Institute for Cancer Research · ATLudwig Boltzmann Institute for Digital Health and Prevention

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This study was set up to evaluate retrospectively the efficacy of a standard diagnostic procedure, including non-invasive and invasive (spinal tap, nerve/muscle biopsy) investigations, in the diagnosis of peripheral neuropathy. The medical records of 171 in-patients with the final diagnosis of peripheral neuropathy of determined or undetermined cause were reviewed and each individual diagnostic work-up was analysed. Basic investigations included the patient's history, a clinical examination and basic laboratory tests. Depending on the individual presentation, course, and severity, further non-invasive and invasive examinations were added according to the department's standard diagnostic procedure. The aetiology could be clarified in 124 patients (73%) and remained unclear in 47 cases. Excluding cases with acute and chronic inflammatory polyneuropathy (n=14), the number of idiopathic peripheral neuropathies dropped to 33. Non-invasive investigations were sufficient to reveal the underlying aetiology in 114 cases (83 %). It is concluded that, with the application of a standard procedure for the diagnosis of peripheral neuropathy, the aetiology can be clarified in 81% of patients. In the other 19% of patients the aetiology remains idiopathic. In the majority of cases, non-invasive investigations were sufficient for diagnosis.

Indexed as

AdultAgedAged, 80 and overElectrophysiologyFemaleHumansMaleMiddle AgedNeuromuscular DiseasesPeripheral Nervous System DiseasesRetrospective Studies

Identifiers

PMID10567598
PMCPMC1741419
OpenAlexW2119417258

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.