ArticleJournal of clinical microbiology1999
Simultaneous infection with two drug-susceptible Mycobacterium tuberculosis strains in an immunocompetent host.
Article in Journal of clinical microbiology, 1999. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.
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Who cites it
16 citing papers in PubMed, 1 synthesis or guideline pooled it, 29 citations in OpenAlex.
- Methods for Detecting Mycobacterial Mixed Strain Infections-A Systematic Review.Frontiers in genetics · 2020Pooled it
- A new method for detecting mixed Mycobacterium tuberculosis infection and reconstructing constituent strains provides insights into transmission.Genome medicine · 2025Article
- Identifying mixed Mycobacterium tuberculosis infections from whole genome sequence data.BMC genomics · 2018Article
- Mixed-strain mycobacterium tuberculosis infections and the implications for tuberculosis treatment and control.Clinical microbiology reviews · 2012Review
- Molecular typing in public health laboratories: from an academic indulgence to an infection control imperative.Journal of preventive medicine and public health = Yebang Uihakhoe chi · 2012Article
- Article
- Mixed infection with Beijing and non-Beijing strains and drug resistance pattern of Mycobacterium tuberculosis.Journal of clinical microbiology · 2010Article
- Molecular detection of mixed infections of Mycobacterium tuberculosis strains in sputum samples from patients in Karonga District, Malawi.Journal of clinical microbiology · 2010Article
- Molecular epidemiology of tuberculosis: toy or tool? A review of the literature and examples from Central Europe.Wiener klinische Wochenschrift · 2007Review
- Evidence for recombination in Mycobacterium tuberculosis.Journal of bacteriology · 2006Article
- Occurrence of overlooked zoonotic tuberculosis: detection of Mycobacterium bovis in human cerebrospinal fluid.Journal of clinical microbiology · 2006Article
- A community outbreak of tuberculosis in Southern Austria: lessons learned for a targeted use of molecular epidemiological methods and tuberculin skin testing.Epidemiology and infection · 2006Article
- Identifying and quantifying genotypes in polyclonal infections due to single species.Emerging infectious diseases · 2006Article
- Reinfection and mixed infection cause changing Mycobacterium tuberculosis drug-resistance patterns.American journal of respiratory and critical care medicine · 2005Article
- Multiple Mycobacterium tuberculosis strains in early cultures from patients in a high-incidence community setting.Journal of clinical microbiology · 2002Article
- Infection of red deer, cattle, and humans with Mycobacterium bovis subsp. caprae in western Austria.Journal of clinical microbiology · 2002Article
Corrections and comments
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
An important assumption for DNA fingerprinting of Mycobacterium tuberculosis is that patients are infected with only one strain at a time. Nonetheless, we demonstrate a case of simultaneous infection with two drug-susceptible strains of M. tuberculosis in an immunocompetent patient by IS6110 restriction fragment length polymorphism and spoligotyping. Epidemiological data prove the patient's involvement in two independent clusters. Thus, double infections should be suspected with fingerprints showing divergent band intensities.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.