ArticleJournal of clinical microbiology1999
Identification of Candida dubliniensis based on temperature and utilization of xylose and alpha-methyl-D-glucoside as determined with the API 20C AUX and vitek YBC systems.
Article in Journal of clinical microbiology, 1999. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 38 papers.
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Who cites it
38 citing papers in PubMed.
- Antifungal Resistance Patterns of Oral and IntestinalMicroorganisms · 2026Article
- Exploring the Biology, Virulence, and General Aspects ofInfection and drug resistance · 2024Review
- gDNA extraction from Candida albicans and Candida dubliniensis in subgingival samples in Argentina. Evaluation of different methods.Acta odontologica latinoamericana : AOL · 2023Article
- Oral yeast colonization in patients with eating disorders: commensal acquisition or due to purgative habits?Revista do Instituto de Medicina Tropical de Sao Paulo · 2020Article
- A Combination Fluorescence Assay Demonstrates Increased Efflux Pump Activity as a Resistance Mechanism in Azole-Resistant Vaginal Candida albicans Isolates.Antimicrobial agents and chemotherapy · 2016Article
- Application of Culture-Independent Rapid Diagnostic Tests in the Management of Invasive Candidiasis and Cryptococcosis.Journal of fungi (Basel, Switzerland) · 2015Review
- Effect of Denture-Related Stomatitis Fluconazole Treatment on Oral Candida albicans Susceptibility Profile and Genotypic Variability.The open dentistry journal · 2015Article
- Third case of Candida dubliniensis endogenous endophthalmitis in North America: case report and review of the literature.International ophthalmology · 2014Review
- The usefulness of DNA sequencing after extraction by Whatman FTA filter matrix technology and phenotypic tests for differentiation of Candida albicans and Candida dubliniensis.Mycopathologia · 2014Article
- Article
- Issues in identifying germ tube positive yeasts by conventional methods.Journal of clinical laboratory analysis · 2014Article
- Article
- Pseudomembranous candidiasis in HIV/AIDS patients in Cali, Colombia.Mycopathologia · 2013Article
- Detection, identification, and distribution of fungi in bronchoalveolar lavage specimens by use of multilocus PCR coupled with electrospray ionization/mass spectrometry.Journal of clinical microbiology · 2013Article
- A simple and reliable PCR-restriction fragment length polymorphism assay to identify Candida albicans and its closely related Candida dubliniensis.Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology] · 2012Article
- First isolation of Candida dubliniensis from oral cavities of dermatological patients in Nanjing, China.Mycopathologia · 2011Article
- Prevalence of Candida dubliniensis fungemia in Argentina: identification by a novel multiplex PCR and comparison of different phenotypic methods.Mycopathologia · 2011Article
- Candida dubliniensis: epidemiology and phenotypic methods for identification.Mycopathologia · 2010Review
- Results from the ARTEMIS DISK Global Antifungal Surveillance Study, 1997 to 2007: a 10.5-year analysis of susceptibilities of Candida Species to fluconazole and voriconazole as determined by CLSI standardized disk diffusion.Journal of clinical microbiology · 2010Article
- Identification of Candida spp. by phenotypic tests and PCR.Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology] · 2010Article
Corrections and comments
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Authors and funding
7 authors.
Funding
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Abstract
To have a better understanding of the role of Candida dubliniensis in clinical infections, it is essential that microbiology laboratories can identify this species rapidly and accurately in clinical specimens. C. dubliniensis has been reported to lack the ability to utilize xylose (XYL) and alpha-methyl-D-glucoside (MDG) and to grow poorly or not at all at 45 degrees C, whereas Candida albicans isolates utilize XYL and MDG and usually grow well at 45 degrees C. We tested 66 isolates of C. dubliniensis and 100 isolates of C. albicans with both the API 20C AUX and Vitek YBC systems to evaluate the ability of the XYL and MDG tests contained within each of these systems to distinguish between the two species. The ability to grow at 45 degrees C was also examined. None of the C. dubliniensis isolates grew at 45 degrees C, and 23 of 100 C. albicans isolates (23%) exhibited poor or no growth at 45 degrees C. The XYL and MDG tests contained within the API 20C AUX system were both negative for all 66 C. dubliniensis isolates and were positive for 98 (XYL) and 56 (MDG) of the 100 C. albicans isolates. With the Vitek system, 64 of 66 C. dubliniensis isolates (97.0%) were XYL negative and 63 (95.0%) were MDG negative. Conversely, 96 of 100 C. albicans isolates (96.0%) were XYL positive and 100 (100.0%) were MDG positive with the Vitek system. Clinical microbiology laboratories could use lack of growth at 45 degrees C and a negative XYL test with either the API 20C AUX or Vitek yeast identification system to provide a presumptive identification of C. dubliniensis. A negative MDG test result with either system would also be helpful but may misclassify C. albicans as C. dubliniensis, especially when the API 20C AUX system is used.
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