ReviewJournal of neuro-oncology1999
Classification, pathogenesis and molecular pathology of primary CNS lymphomas.
Review in Journal of neuro-oncology, 1999. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
16 citing papers in PubMed, 1 synthesis or guideline pooled it, 81 citations in OpenAlex.
- The role of additional radiotherapy for primary central nervous system lymphoma.The Cochrane database of systematic reviews · 2014Pooled it
- Cultured Cells Isolated from CNS Indolent B-Cell Lymphoma Have Characteristics of Mesenchymal Stem Cells: A Clinical Case and Scientific Research.International journal of hematology-oncology and stem cell research · 2018Article
- Stat3-positive tumor cells contribute to vessels neoformation in primary central nervous system lymphoma.Oncotarget · 2017Article
- Diagnostic vitrectomy for primary intraocular lymphoma: when, why, how?International ophthalmology clinics · 2014Review
- Article
- Primary pituitary lymphoma in an immunocompetent patient: a rare clinical entity.Journal of neurology · 2012Article
- Prognostic value of immunohistochemical profile and response to high-dose methotrexate therapy in primary CNS lymphoma.Journal of neuro-oncology · 2010Article
- Angiogenesis in primary central nervous system lymphoma (PCNSL).Journal of neuro-oncology · 2007Article
- [Primary CNS lymphoma in azathioprine therapy for autoimmune diseases: review of the literature and case report].Der Nervenarzt · 2007Review
- Detection of the bcl-2 t(14;18) translocation and proto-oncogene expression in primary intraocular lymphoma.Investigative ophthalmology & visual science · 2006Article
- A 19-year-old male with generalized seizures, unconsciousness and a deviation of gaze.Brain pathology (Zurich, Switzerland) · 2006Article
- Primary central nervous system lymphoma.Current oncology reports · 2004Review
- Analysis of chromosomal copy number changes and oncoprotein expression in primary central nervous system lymphomas: frequent loss of chromosome arm 6q.Virchows Archiv : an international journal of pathology · 2003Article
- Molecular pathology of primary intraocular lymphoma.Transactions of the American Ophthalmological Society · 2003Article
- Intraocular lymphoma: update on diagnosis and management.Cancer control : journal of the Moffitt Cancer CenterReview
- Primary testicular and intraocular lymphomas: two case reports and a review of the literature.Survey of ophthalmologyArticle
Corrections and comments
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Authors and funding
1 author at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Classification, pathogenesis and molecular pathology of primary central nervous system lymphomas (PCNSL) pose major clinico-pathologic problems. Application of histopathologic classification schemes developed for nodal lymphomas, i.e. the Kiel Classification and the Working Formulation, is not reliable and clinically not relevant for PCNSL. The more recent REAL Classification will simplify subtyping of PCNSL, but reliability and clinical significance remain to be determined. There are virtually no experimental data on whether PCNSL develop outside of the brain, or whether they arise from polyclonal lymphoproliferations within the brain. Mutations of oncogenes and tumor suppressor genes have been analyzed in only a few tumors, and their type and frequency is essentially unknown. In conclusion, compared with both neuroectodermal brain tumors and nodal lymphomas, and given the increasing incidence and clinical impact of PCNSL, there is a remarkable lack of histopathologic consensus as well as a surprising shortage of pathogenetic and molecular genetic information.
Indexed as
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.