ReviewOncogene1999
Regulated nuclear localization of stress-responsive factors: how the nuclear trafficking of protein kinases and transcription factors contributes to cell survival.
Review in Oncogene, 1999. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
16 citing papers in PubMed, 45 citations in OpenAlex.
- Bifunctional Small Molecules That Induce Nuclear Localization and Targeted Transcriptional Regulation.Journal of the American Chemical Society · 2023Article
- Bifunctional small molecules that induce nuclear localization and targeted transcriptional regulation.bioRxiv : the preprint server for biology · 2023Article
- Cytoplasmic sequestration of p53 by lncRNA-CIRPILalleviates myocardial ischemia/reperfusion injury.Communications biology · 2022Article
- The p38 Pathway: From Biology to Cancer Therapy.International journal of molecular sciences · 2020Review
- Development of Cell-Permeable, Non-Helical Constrained Peptides to Target a Key Protein-Protein Interaction in Ovarian Cancer.Angewandte Chemie (International ed. in English) · 2017Article
- Hepatitis C Virus RNA-Dependent RNA Polymerase Interacts with the Akt/PKB Kinase and Induces Its Subcellular Relocalization.Antimicrobial agents and chemotherapy · 2016Article
- High-Salt Enhances the Inflammatory Response by Retina Pigment Epithelium Cells following Lipopolysaccharide Stimulation.Mediators of inflammation · 2015Article
- Potential effects of CRM1 inhibition in mantle cell lymphoma.Chinese journal of cancer research = Chung-kuo yen cheng yen chiu · 2012Article
- Nuclear and mitochondrial signalling Akts in cardiomyocytes.Cardiovascular research · 2009Review
- Nucleocytoplasmic trafficking of G2/M regulators in yeast.Molecular biology of the cell · 2008Article
- Cellular localization and role of kinase activity of PMK1 in Magnaporthe grisea.Eukaryotic cell · 2004Article
- Modulation of retinoid signaling by a cytoplasmic viral protein via sequestration of Sp110b, a potent transcriptional corepressor of retinoic acid receptor, from the nucleus.Molecular and cellular biology · 2003Article
- Sequence conserved for subcellular localization.Protein science : a publication of the Protein Society · 2002Article
- Dealing with osmostress through MAP kinase activation.EMBO reports · 2002Review
- Ultrastructural localization of rRNA shows defective nuclear export of preribosomes in mutants of the Nup82p complex.The Journal of cell biology · 2001Article
- Aging-associated truncated form of p53 interacts with wild-type p53 and alters p53 stability, localization, and activity.Mechanisms of ageing and developmentArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The details of nuclear transport mechanisms are emerging rapidly, largely through work with model organisms. Here, we briefly describe these advances, with an emphasis on the remaining challenges. We then address the nuclear transport of some high profile cellular regulators, including p53 and the proto-oncogene PKB/Akt. We discuss the mechanisms that contribute to the differential subcellular localization of these proteins. Finally, we analyse the provocative patterns that emerge from our overview.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.