Evidence map›Paper›PMID 10554532›Full record

Trial reportMedizinische Klinik (Munich, Germany : 1983)1999

[Molecular biology studies of a multicenter phase III study (SIC Study)].

T Zimmermann, S Albrecht, G von Gagern

Abstract readClinical TrialClinical Trial, Phase IIIEnglish Abstract
PubMed Publisher
In one paragraph

Trial report in Medizinische Klinik (Munich, Germany : 1983), 1999. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Selenium supplementation for critically ill adults.The Cochrane database of systematic reviews · 2015
    Pooled it
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

T ZimmermannKlinik und Poliklinik für Viszeral-, Thorax- und Gefässchirurgie, Universitätsklinikums, TU Dresden. zialblcl@rcs.urz.tu-dresden.de
S Albrecht
G von Gagern

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Transcription factors adjust the up- and downregulation of inflammatory genes. Within the bounds of the SIC-study (Selenium in Intensive Care) the authors will investigate the role of transcription factors NF-kappa B and AP-1 in S.I.R.S/septic patients. The goal of these investigations is the corroboration of therapy of septic patients with sodium selenite at the molecular biological level.

Indexed as

Critical CareDown-RegulationHumansNF-kappa BSodium SeleniteSystemic Inflammatory Response SyndromeTranscription Factor AP-1Up-RegulationNF-kappa BSodium SeleniteTranscription Factor AP-1

Identifiers

PMID10554532

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.