Evidence map›Paper›PMID 10550992›Full record

ReviewProgress in brain research1999

Molecular recognition in P2 receptors: ligand development aided by molecular modeling and mutagenesis.

K A Jacobson, C Hoffmann, Y C Kim, E Camaioni, E Nandanan, S Y Jang, D P Guo, X D Ji, I von Kügelgen, S Moro and 9 more

Abstract readReview
In one paragraph

Review in Progress in brain research, 1999. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Review
  2. Review
  3. Review
  4. Article
  5. Article
  6. Article
  7. Purine and pyrimidine (P2) receptors as drug targets.Journal of medicinal chemistry · 2002
    Review
  8. Actions of a Series of PPADS Analogs at P2XDrug development research · 2001
    Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors.

K A JacobsonMolecular Recognition Section, LBC, NIDDK, NIH, Bethesda, MD 20892, USA. kajacobs@helix.nih.gov
C Hoffmann
Y C Kim
E Camaioni
E Nandanan
S Y Jang
D P Guo
X D Ji
I von Kügelgen
S Moro
A U Ziganshin
A Rychkov
B F King
S G Brown
S S Wildman
G Burnstock
J L Boyer
A Mohanram
T K Harden

Funding

Drugs that Act at Adenosine ReceptorsZ01DK031117 · NIDDK · NATIONAL INSTITUTE OF DIABETES AND DIGESTIVE AND KIDNEY DISEASES · PI JACOBSON, KENNETH ALAN · 1991 to 2008
$854k
PROSTHETIC GROUPS FOR RADIOLABELING OF FUNCTIONALIZED DRUGS AND PEPTIDESZ01DK031116 · NIDDK · NATIONAL INSTITUTE OF DIABETES AND DIGESTIVE AND KIDNEY DISEASES · PI JACOBSON, KENNETH ALAN · 1991 to 2008
$769k
FUNCTIONALIZED CONGENERS OF BIOACTIVE COMPOUNDSZ01DK031115 · NIDDK · NATIONAL INSTITUTE OF DIABETES AND DIGESTIVE AND KIDNEY DISEASES · PI JACOBSON, KENNETH ALAN · 1991 to 2008
$577k
Development of Drugs Acting at Ion ChannelsZ01DK031127 · NIDDK · NATIONAL INSTITUTE OF DIABETES AND DIGESTIVE AND KIDNEY DISEASES · PI JACOBSON, KENNETH ALAN · 2007 to 2008
$385k
Intramural NIH HHS Z01 DK031116Intramural NIH HHS Z01 DK031127Intramural NIH HHS Z99 DK999999
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Adenosine TriphosphateAmino Acid SequenceAnimalsHumansLigandsModels, MolecularMolecular Sequence DataMutagenesis, Site-DirectedProtein ConformationReceptors, Purinergic P2Adenosine TriphosphateLigandsReceptors, Purinergic P2

Identifiers

PMID10550992
PMCPMC4321826

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.