ArticleThe Journal of pediatrics1999
Viral infections in interferon-gamma receptor deficiency.
Article in The Journal of pediatrics, 1999. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 58 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
58 citing papers in PubMed, 176 citations in OpenAlex.
- A digenic human immunodeficiency characterized by IFNAR1 and IFNGR2 mutations.The Journal of clinical investigation · 2017Trial
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- The interplay of tuberculosis and COVID-19: Insights into global health challenges.Journal of biosciences · 2025Review
- A robust mouse model of HPIV-3 infection and efficacy of GS-441524 against virus-induced lung pathology.Nature communications · 2024Article
- Anti-Interferon-γ Therapy for Cytokine Storm Syndromes.Advances in experimental medicine and biology · 2024Review
- Bacterial-induced or passively administered interferon gamma conditions the lung for early control of SARS-CoV-2.Nature communications · 2023Article
- Interferons-Implications in the Immune Response to Respiratory Viruses.Microorganisms · 2023Review
- Systemic aspergillosis in a patient with interferon gamma receptor 1 deficiency; a case report.BMC pediatrics · 2023Article
- IFN-γ lowers tumor growth by increasing glycolysis and lactate production in a nitric oxide-dependent manner: implications for cancer immunotherapy.Frontiers in immunology · 2023Article
- Immunity to Cryptosporidium: Lessons from Acquired and Primary Immunodeficiencies.Journal of immunology (Baltimore, Md. : 1950) · 2022Article
- The lung in inborn errors of immunity: From clinical disease patterns to molecular pathogenesis.The Journal of allergy and clinical immunology · 2022Review
- Transcriptional response to VZV infection is modulated by RNA polymerase III in lung epithelial cell lines.Frontiers in cellular and infection microbiology · 2022Article
- Targeting interferon-γ in hyperinflammation: opportunities and challenges.Nature reviews. Rheumatology · 2021Review
- Clinical and Molecular Findings in Mendelian Susceptibility to Mycobacterial Diseases: Experience From India.Frontiers in immunology · 2021Article
- Genetic influences on viral-induced cytokine responses in the lung.Mucosal immunology · 2021Review
- Genetic Lesions of Type I Interferon Signalling in Human Antiviral Immunity.Trends in genetics : TIG · 2021Review
- A case of recurrent herpes simplex 2 encephalitis, VZV reactivations, and dominant partial interferon-gamma-receptor-1 deficiency supports relevance of IFNgamma for antiviral defense in humans.Molecular and cellular pediatrics · 2020Article
- Article
- Human inborn errors of immunity to herpes viruses.Current opinion in immunology · 2020Review
- Exportin-1-Dependent Nuclear Export of DEAD-box Helicase DDX3X is Central to its Role in Antiviral Immunity.Cells · 2019Article
Corrections and comments
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Authors and funding
10 authors at 4 institutions in 2 countries.
Funding
Abstract
Interferon-gamma receptor deficiency is a recently described immunodeficiency that is associated with onset of severe mycobacterial infections in childhood. We describe the occurrence of symptomatic and often severe viral infections in 4 patients with interferon-gamma receptor deficiency and mycobacterial disease. The viral pathogens included herpes viruses, parainfluenza virus type 3, and respiratory syncytial virus. We conclude that patients with interferon-gamma receptor deficiency and mycobacterial disease have increased susceptibility to some viral pathogens.
Indexed as
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.