ArticleProceedings of the National Academy of Sciences of the United States of America1999
Genetic ablation of root cap cells in Arabidopsis.
Article in Proceedings of the National Academy of Sciences of the United States of America, 1999. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 69 papers.
What it found
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Who cites it
69 citing papers in PubMed.
- Both brefeldin A and latrunculin B treatment induces cytoplasmic aggregation of plasma membrane-associated proteins in epidermal cells, but not in columella cells.Plant signaling & behavior · 2026Article
- A versatile inducible plant model system for dissecting p53 function and discovering novel interaction networks.iScience · 2026Article
- Regulation of shoot gravitropism and branching angle by the GRV2-SAC1 axis in Arabidopsis.The Plant journal : for cell and molecular biology · 2026Article
- An RbohC and RbohE-mediated ROS oscillatory circuit regulates root cap turnover in Arabidopsis.iScience · 2025Article
- Auxin transport positions stem cells in the vascular cambium during normal development and regeneration.Proceedings of the National Academy of Sciences of the United States of America · 2025Article
- The PIN2 ortholog in barley modifies root gravitropism and architecture.The plant genome · 2025Article
- Female gametophyte development is required for nucellar-tip degeneration during Arabidopsis ovule development.Planta · 2024Article
- Article
- Gravity sensing and responses in the coordination of the shoot gravitropic setpoint angle.The New phytologist · 2022Review
- Application of Green-enhanced Nano-lantern as a bioluminescent ratiometric indicator for measurement of Arabidopsis thaliana root apoplastic fluid pH.Plant, cell & environment · 2022Article
- New Insights Into the Activity of Apple Dihydrochalcone Phloretin: Disturbance of Auxin Homeostasis as Physiological Basis of Phloretin Phytotoxic Action.Frontiers in plant science · 2022Article
- Article
- The quiescent center and root regeneration.Journal of experimental botany · 2021Article
- Article
- The Mildew Resistance Locus O 4 Interacts with CaM/CML and Is Involved in Root Gravity Response.International journal of molecular sciences · 2021Article
- Cytokinin-Controlled Gradient Distribution of Auxin inInternational journal of molecular sciences · 2021Review
- Auxin and Root Gravitropism: Addressing Basic Cellular Processes by Exploiting a Defined Growth Response.International journal of molecular sciences · 2021Review
- Article
- Integrative Roles of Phytohormones on Cell Proliferation, Elongation and Differentiation in theFrontiers in plant science · 2021Review
- Intricate genetic variation networks control the adventitious root growth angle in apple.BMC genomics · 2020Article
9 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The root cap is increasingly appreciated as a complex and dynamic plant organ. Root caps sense and transmit environmental signals, synthesize and secrete small molecules and macromolecules, and in some species shed metabolically active cells. However, it is not known whether root caps are essential for normal shoot and root development. We report the identification of a root cap-specific promoter and describe its use to genetically ablate root caps by directing root cap-specific expression of a diphtheria toxin A-chain gene. Transgenic toxin-expressing plants are viable and have normal aerial parts but agravitropic roots, implying loss of root cap function. Several cell layers are missing from the transgenic root caps, and the remaining cells are abnormal. Although the radial organization of the roots is normal in toxin-expressing plants, the root tips have fewer cytoplasmically dense cells than do wild-type root tips, suggesting that root meristematic activity is lower in transgenic than in wild-type plants. The roots of transgenic plants have more lateral roots and these are, in turn, more highly branched than those of wild-type plants. Thus, root cap ablation alters root architecture both by inhibiting root meristematic activity and by stimulating lateral root initiation. These observations imply that the root caps contain essential components of the signaling system that determines root architecture.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.