Evidence map›Paper›PMID 10535605›Full record

ReviewJournal of clinical immunology1999

HIV infection and pathogenesis: what about chemokines?

R C Gallo, A Garzino-Demo, A L DeVico

Abstract readReview
PubMed Publisher
In one paragraph

Review in Journal of clinical immunology, 1999. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
1.0field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 38 citations in OpenAlex.

  1. Trial
  2. Article
  3. Article
  4. Soluble factors from T cells inhibiting X4 strains of HIV are a mixture of β chemokines and RNases.Proceedings of the National Academy of Sciences of the United States of America · 2012
    Article
  5. Article
  6. Genetic correlates influencing immunopathogenesis of HIV infection.The Indian journal of medical research · 2011
    Review
  7. Review
  8. Article
  9. Review
  10. Review
  11. Human genes that limit AIDS.Nature genetics · 2004
    Review
  12. Review
  13. Modulating influence on HIV/AIDS by interacting RANTES gene variants.Proceedings of the National Academy of Sciences of the United States of America · 2002
    Article
  14. Global survey of genetic variation in CCR5, RANTES, and MIP-1alpha: impact on the epidemiology of the HIV-1 pandemic.Proceedings of the National Academy of Sciences of the United States of America · 2001
    Article
  15. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

R C GalloUniversity of Maryland Biotechnology Institute, University of Maryland, Baltimore 21201-1192, USA. coleman@umbi.umd.edu
A Garzino-Demo
A L DeVico
University of Maryland, Baltimore · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Several chemotactic cytokines, or chemokines. inhibit HIV replication by blocking or down regulating chemokine receptors that serve as entry cofactors for the virus. Although the role of chemokine receptors in HIV pathogenesis has been the subject of intense interest, chemokines are comparatively less seriously considered as potential correlates of protection from HIV infection and disease progression. However, a critical analysis of newly available data reveals substantial evidence to support a beneficial role for chemokines in HIV infection and disease. In this review we summarize the results of such studies and their promising implications for HIV infection.

Indexed as

AnimalsChemokinesHIVHIV InfectionsHumansChemokines

Identifiers

PMID10535605
OpenAlexW94782037

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.