ArticleThe Journal of cell biology1999
The maize tha4 gene functions in sec-independent protein transport in chloroplasts and is related to hcf106, tatA, and tatB.
Article in The Journal of cell biology, 1999. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
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Who cites it
18 citing papers in PubMed.
- Localization of proteins involved in the biogenesis and repair of the photosynthetic apparatus to thylakoid subdomains inPlant direct · 2024Article
- Article
- The ten amino acids of the oxygen-evolving enhancer of tobacco is sufficient as the peptide residues for protein transport to the chloroplast thylakoid.Plant molecular biology · 2021Article
- A short PPR protein required for the splicing of specific group II introns in angiosperm chloroplasts.RNA (New York, N.Y.) · 2012Article
- Parallel pigment and transcriptomic analysis of four barley albina and xantha mutants reveals the complex network of the chloroplast-dependent metabolism.Plant molecular biology · 2009Article
- Clustering of C-terminal stromal domains of Tha4 homo-oligomers during translocation by the Tat protein transport system.Molecular biology of the cell · 2009Article
- A stromal pool of TatA promotes Tat-dependent protein transport across the thylakoid membrane.The Journal of biological chemistry · 2008Article
- Large-scale translocation reversal within the thylakoid Tat system in vivo.The Journal of cell biology · 2005Article
- Maize mutants lacking chloroplast FtsY exhibit pleiotropic defects in the biogenesis of thylakoid membranes.The Plant cell · 2004Article
- MFP1 is a thylakoid-associated, nucleoid-binding protein with a coiled-coil structure.Nucleic acids research · 2003Article
- Thylakoid targeting of Tat passenger proteins shows no delta pH dependence in vivo.The EMBO journal · 2003Article
- A twin arginine signal peptide and the pH gradient trigger reversible assembly of the thylakoid [Delta]pH/Tat translocase.The Journal of cell biology · 2002Article
- Central functions of the lumenal and peripheral thylakoid proteome of Arabidopsis determined by experimentation and genome-wide prediction.The Plant cell · 2002Article
- Arabidopsis genes essential for seedling viability: isolation of insertional mutants and molecular cloning.Genetics · 2001Article
- An essential role of a TatC homologue of a Delta pH- dependent protein transporter in thylakoid membrane formation during chloroplast development in Arabidopsis thaliana.Proceedings of the National Academy of Sciences of the United States of America · 2001Article
- Thylakoid DeltapH-dependent precursor proteins bind to a cpTatC-Hcf106 complex before Tha4-dependent transport.The Journal of cell biology · 2001Article
- Article
- Biogenesis of the chloroplast-encoded D1 protein: regulation of translation elongation, insertion, and assembly into photosystem II.The Plant cell · 2000Article
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Authors and funding
5 authors.
Funding
Abstract
Proteins are translocated across the chloroplast thylakoid membrane by a variety of mechanisms. Some proteins engage a translocation machinery that is derived from the bacterial Sec export system and require an interaction with a chloroplast-localized SecA homologue. Other proteins engage a machinery that is SecA-independent, but requires a transmembrane pH gradient. Recently, a counterpart to this Delta pH mechanism was discovered in bacteria. Genetic studies revealed that one maize protein involved in this mechanism, HCF106, is related in both structure and function to the bacterial tatA and tatB gene products. We describe here the mutant phenotype and molecular cloning of a second maize gene that functions in the Delta pH mechanism. This gene, thylakoid assembly 4 (tha4), is required specifically for the translocation of proteins that engage the Delta pH pathway. The sequence of the tha4 gene product resembles those of the maize hcf106 gene and the bacterial tatA and tatB genes. Sequence comparisons suggest that tha4 more closely resembles tatA, and hcf106 more closely resembles tatB. These findings support the notion that this sec-independent translocation mechanism has been highly conserved during the evolution of eucaryotic organelles from bacterial endosymbionts.
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