ArticleThe Plant cell1999
An Arabidopsis cell cycle -dependent kinase-related gene, CDC2b, plays a role in regulating seedling growth in darkness.
Article in The Plant cell, 1999. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.
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Who cites it
24 citing papers in PubMed, 74 citations in OpenAlex.
- Characterization of a High Hierarchical Regulator,Frontiers in plant science · 2021Article
- The Control of Cell Expansion, Cell Division, and Vascular Development by Brassinosteroids: A Historical Perspective.International journal of molecular sciences · 2020Review
- Functional Characterization of Populus PsnSHN2 in Coordinated Regulation of Secondary Wall Components in Tobacco.Scientific reports · 2017Article
- Global Transcriptome Profiling Analysis of Inhibitory Effects of Paclobutrazol on Leaf Growth in Lily (Lilium Longiflorum-Asiatic Hybrid).Frontiers in plant science · 2016Article
- Does the upstream region possessing MULE-like sequence in rice upregulate PsbS1 gene expression?PloS one · 2014Article
- Systemic control of cell division and endoreduplication by NAA and BAP by modulating CDKs in root tip cells of Allium cepa.BioMed research international · 2014Article
- Brassinosteroid perception in the epidermis controls root meristem size.Development (Cambridge, England) · 2011Article
- Article
- VND-INTERACTING2, a NAC domain transcription factor, negatively regulates xylem vessel formation in Arabidopsis.The Plant cell · 2010Article
- Functional evolution of cyclin-dependent kinases.Molecular biotechnology · 2009Review
- Transcriptome analysis of proliferating Arabidopsis endosperm reveals biological implications for the control of syncytial division, cytokinin signaling, and gene expression regulation.Plant physiology · 2008Article
- A role of brassinosteroids in early fruit development in cucumber.Journal of experimental botany · 2008Article
- Heterologous expression and molecular and cellular characterization of CaPUB1 encoding a hot pepper U-Box E3 ubiquitin ligase homolog.Plant physiology · 2006Article
- Increased level of polyploidy1, a conserved repressor of CYCLINA2 transcription, controls endoreduplication in Arabidopsis.The Plant cell · 2006Article
- The plant-specific cyclin-dependent kinase CDKB1;1 and transcription factor E2Fa-DPa control the balance of mitotically dividing and endoreduplicating cells in Arabidopsis.The Plant cell · 2004Article
- Role of an atypical E2F transcription factor in the control of Arabidopsis cell growth and differentiation.The Plant cell · 2004Article
- B1-type cyclin-dependent kinases are essential for the formation of stomatal complexes in Arabidopsis thaliana.The Plant cell · 2004Article
- Three redundant brassinosteroid early response genes encode putative bHLH transcription factors required for normal growth.Genetics · 2002Article
- Variation in growth rate between Arabidopsis ecotypes is correlated with cell division and A-type cyclin-dependent kinase activity.Plant physiology · 2002Article
- Brassinosteroids and plant steroid hormone signaling.The Plant cell · 2002Review
Corrections and comments
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Authors and funding
4 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The Arabidopsis CDC2b gene has been defined as a plant-specific cell cycle-dependent kinase-related gene, although it lacks the conserved cyclin binding motif, and its exact function is not known. Here, we report that in etiolated seedlings, the expression of the CDC2b gene is correlated with elongation rate of the hypocotyl. Inhibition of CDC2b gene expression by using an inducible antisense construct resulted in short-hypocotyl and open-cotyledon phenotypes when transgenic seedlings were grown in the dark. The severity of these phenotypes in dark-grown seedlings could be correlated with the level of the antisense gene expression. The short hypocotyl of seedlings underexpressing CDC2b was a result of inhibition of cell elongation rather than a reduction in cell number, whereas in cotyledons, inhibition of CDC2b expression resulted in large, open cotyledons with amyloplasts rather than etioplasts. Although the nuclear DNA was less compact in the antisense hypocotyl cells, DNA content and endoreduplication were not affected. Cell division of the shoot apical meristem also was not affected by antisense expression. The short-hypocotyl phenotype of these transgenic plants was partially rescued by the addition of brassinolide. Brassinolide can only induce CDC2b expression in darkness. These results suggest a role for the CDC2b gene in seedling growth via regulation of hypocotyl cell elongation and cotyledon cell development.
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