ArticleAmerican journal of human genetics1999
A complete genome screen in sib pairs affected by Gilles de la Tourette syndrome. The Tourette Syndrome Association International Consortium for Genetics.
Article in American journal of human genetics, 1999. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 45 papers.
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Who cites it
45 citing papers in PubMed.
- Reward enhances tic suppression in children within months of tic disorder onset.Developmental cognitive neuroscience · 2015Trial
- Trial
- Provisional Tic Disorder is not so transient.Scientific reports · 2019Article
- Genetic and phenotypic overlap of specific obsessive-compulsive and attention-deficit/hyperactive subtypes with Tourette syndrome.Psychological medicine · 2018Article
- Progress in Genetic Studies of Tourette's Syndrome.Brain sciences · 2017Review
- Article
- Identification of Two Heritable Cross-Disorder Endophenotypes for Tourette Syndrome.The American journal of psychiatry · 2017Article
- Article
- A Review and Update on Tourette Syndrome: Where Is the Field Headed?Current neurology and neuroscience reports · 2016Review
- Transcriptome Analysis of the Human Striatum in Tourette Syndrome.Biological psychiatry · 2016Article
- VISIT-TS: A multimedia tool for population studies on tic disorders.F1000Research · 2016Article
- Tourette Syndrome: Bridging the Gap between Genetics and Biology.Molecular neuropsychiatry · 2015Article
- The Tourette International Collaborative Genetics (TIC Genetics) study, finding the genes causing Tourette syndrome: objectives and methods.European child & adolescent psychiatry · 2015Article
- Association of the KCNJ5 gene with Tourette Syndrome and Attention-Deficit/Hyperactivity Disorder.Genes, brain, and behavior · 2014Article
- Prevalence and clinical correlates of explosive outbursts in Tourette syndrome.Psychiatry research · 2013Article
- Pathogenetic model for Tourette syndrome delineates overlap with related neurodevelopmental disorders including Autism.Translational psychiatry · 2012Review
- The genetics of Tourette syndrome.Nature reviews. Neurology · 2012Review
- The familial association of tourette's disorder and ADHD: the impact of OCD symptoms.American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics · 2011Article
- The genetics of Tourette disorder.Current opinion in genetics & development · 2011Review
- Familiality of Tourette syndrome, obsessive-compulsive disorder, and attention-deficit/hyperactivity disorder: heritability analysis in a large sib-pair sample.Journal of the American Academy of Child and Adolescent Psychiatry · 2011Article
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Abstract
Gilles de la Tourette syndrome is a neuropsychiatric disorder characterized by waxing and waning multiple motor and phonic tics with a complex mode of inheritance. Previous attempts, which used large multigenerational families to localize susceptibility loci, have been unsuccessful. In this report, the results of the first systematic genome scan, using 76 affected-sib-pair families with a total of 110 sib pairs, are summarized. While no results reached acceptable statistical significance, the multipoint maximum-likelihood scores (MLS) for two regions (4q and 8p) were suggestive (MLS > 2.0). Four additional genomic regions also gave multipoint MLS scores between 1.0 and 2.0.
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