ReviewClinical microbiology reviews1999
Plant products as antimicrobial agents.
Review in Clinical microbiology reviews, 1999. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1,417 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1,417 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Antimicrobial potential of selected medicinal plants against drug-resistant pathogens: a systematic review.Frontiers in pharmacology · 2026Pooled it
- ManagingMolecules (Basel, Switzerland) · 2025Pooled it
- Chemical Profiling by UHPLC-MS/MS and In Vitro Antioxidant, Antimicrobial, and Cytotoxic Properties of Lepidoceras peruvianum Kuijt Leaves and Fruits.Rapid communications in mass spectrometry : RCM · 2026Article
- Antibacterial efficacy of Cassia seena sp. leaf extracts against Staphylococcus aureus and Escherichia coli: a phytochemical and toxicological evaluation.Folia microbiologica · 2026Article
- HarnessingFood science & nutrition · 2026Review
- Article
- From Antimicrobial Activity to Topical Translation: An Integrated Framework for Testing, Cytotoxicity Assessment and Formulation of Plant Extracts, Essential Oils and Honey.Pharmaceutics · 2026Review
- Green Synthesis of Silver Nanoparticles From Various Leaves Extract: Antioxidant, Anti-Inflammatory, Antibacterial Activities and Inhibitory Effect on Glutathione S-Transferase.Food science & nutrition · 2026Article
- Development of a Biodegradable Polysaccharide-Based Polymer Film FromFood science & nutrition · 2026Article
- Antifungal and Profungal Potentials of Acetone-Extracted Complexes of Lichen Substances on MacromyceteMolecules (Basel, Switzerland) · 2026Article
- Spray-Dried Eugenol Microparticles: Physicochemical Characterization and Enhanced Antibacterial Activity.Pharmaceuticals (Basel, Switzerland) · 2026Article
- Plant-Based Therapeutics Against Communicable Diseases: A Review of Ethnopharmacology and Medicinal Chemistry Approaches.Chemistry & biodiversity · 2026Review
- Integrated Phytochemical Profiling, Spectroscopic Analysis, and Molecular Docking Evaluation of Ethanolic Plant Extracts Against Candida Receptor (1IYK).Journal of fungi (Basel, Switzerland) · 2026Article
- Article
- Plant-part specific in vitro antibacterial activity of crude ethanolic extracts of Mangifera indica against Salmonella typhi: an exploratory study.BMC complementary medicine and therapies · 2026Article
- Chlorophyll a fluorescence and biochemical analyses to probe the impacts of artificial light at night on certain ornamental plant species.Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology · 2026Article
- Article
- Local Endemic Cirsium boluense: Antimutagenic, Antioxidant, and Antibacterial Activities and Phenolic Profiles of Plant Parts.Chemistry & biodiversity · 2026Article
- Green fabrication of silver nanoparticles using Corallocarpus epigaeus (Hook.f.) Cogn. rhizome extract: phytochemical characterization and evaluation of antioxidant, antimicrobial, and anticancer activity against HT-29 cells.Journal of molecular histology · 2026Article
- From Ethnobotany to Pharmacognosy: A Review ofPlants (Basel, Switzerland) · 2026Review
1,357 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The use of and search for drugs and dietary supplements derived from plants have accelerated in recent years. Ethnopharmacologists, botanists, microbiologists, and natural-products chemists are combing the Earth for phytochemicals and "leads" which could be developed for treatment of infectious diseases. While 25 to 50% of current pharmaceuticals are derived from plants, none are used as antimicrobials. Traditional healers have long used plants to prevent or cure infectious conditions; Western medicine is trying to duplicate their successes. Plants are rich in a wide variety of secondary metabolites, such as tannins, terpenoids, alkaloids, and flavonoids, which have been found in vitro to have antimicrobial properties. This review attempts to summarize the current status of botanical screening efforts, as well as in vivo studies of their effectiveness and toxicity. The structure and antimicrobial properties of phytochemicals are also addressed. Since many of these compounds are currently available as unregulated botanical preparations and their use by the public is increasing rapidly, clinicians need to consider the consequences of patients self-medicating with these preparations.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.