ArticleAntimicrobial agents and chemotherapy1999
Drug efflux and parC mutations are involved in fluoroquinolone resistance in viridans group streptococci.
Article in Antimicrobial agents and chemotherapy, 1999. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
What it found
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Who cites it
18 citing papers in PubMed, 30 citations in OpenAlex.
- Role of PatAB Transporter in Efflux of Levofloxacin inAntibiotics (Basel, Switzerland) · 2022Article
- Upregulation of the PatAB Transporter Confers Fluoroquinolone Resistance toFrontiers in microbiology · 2017Article
- Alterations in the Quinolone Resistance-Determining Regions and Fluoroquinolone Resistance in Clinical Isolates and Laboratory-Derived Mutants of Mycoplasma bovis: Not All Genotypes May Be Equal.Applied and environmental microbiology · 2016Article
- Absence of tmRNA Has a Protective Effect against Fluoroquinolones inFrontiers in microbiology · 2016Article
- Emergence of ciprofloxacin-nonsusceptible Streptococcus pyogenes isolates from healthy children and pediatric patients in Portugal.Antimicrobial agents and chemotherapy · 2010Article
- Changes in fluoroquinolone-resistant Streptococcus pneumoniae after 7-valent conjugate vaccination, Spain.Emerging infectious diseases · 2009Article
- Emergence of quinolone resistance among viridans group streptococci isolated from the oropharynx of neutropenic peripheral blood stem cell transplant patients receiving quinolone antimicrobial prophylaxis.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2005Article
- Interspecies recombination in type II topoisomerase genes is not a major cause of fluoroquinolone resistance in invasive Streptococcus pneumoniae isolates in the United States.Antimicrobial agents and chemotherapy · 2005Article
- Fluoroquinolone resistance in penicillin-resistant Streptococcus pneumoniae clones, Spain.Emerging infectious diseases · 2004Article
- Viridans group streptococci are donors in horizontal transfer of topoisomerase IV genes to Streptococcus pneumoniae.Antimicrobial agents and chemotherapy · 2003Article
- In vitro antibacterial activity and pharmacodynamics of new quinolones.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2003Review
- Evidence of active efflux in resistance to ciprofloxacin and to ethidium bromide by Mycoplasma hominis.Antimicrobial agents and chemotherapy · 2002Article
- Interspecies recombination contributes minimally to fluoroquinolone resistance in Streptococcus pneumoniae.Antimicrobial agents and chemotherapy · 2001Article
- gyrA mutations associated with quinolone resistance in Bacteroides fragilis group strains.Antimicrobial agents and chemotherapy · 2001Article
- In vitro development of resistance to six quinolones in Streptococcus pneumoniae, Streptococcus pyogenes, and Staphylococcus aureus.Antimicrobial agents and chemotherapy · 2001Article
- Efflux-mediated resistance to fluoroquinolones in gram-positive bacteria and the mycobacteria.Antimicrobial agents and chemotherapy · 2000Review
- Fluoroquinolone resistance associated with target mutations and active efflux in oropharyngeal colonizing isolates of viridans group streptococci.Antimicrobial agents and chemotherapy · 2000Article
- Horizontal transfer of parC and gyrA in fluoroquinolone-resistant clinical isolates of Streptococcus pneumoniae.Antimicrobial agents and chemotherapy · 2000Article
Corrections and comments
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Authors and funding
5 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Nine ciprofloxacin-resistant viridans group streptococci isolated from asymptomatic carriers were analyzed. Identification to the species level by using three different commercial systems and a PCR-based approach was inconsistent. The nucleotide sequences of fragments of the parC, parE, gyrA, and gyrB genes showed considerable intra- and interspecies variations, and these variations mainly involved silent mutations. Three isolates had changes in Ser-79 of ParC (to Phe or Tyr). Phenotypic characterization indicated that eight of the nine isolates had a putative efflux mechanism that would confer low-level resistance to ciprofloxacin.
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