Trial reportNeuroscience and behavioral physiology
Pain sensitivity in chronic psychoemotional stress in humans.
Trial report in Neuroscience and behavioral physiology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
11 citing papers in PubMed, 40 citations in OpenAlex.
- Neuroimmune Interactions in Pain and Stress: An Interdisciplinary Approach.The Neuroscientist : a review journal bringing neurobiology, neurology and psychiatry · 2021Review
- Hand-Feel Touch Cues and Their Influences on Consumer Perception and Behavior with Respect to Food Products: A Review.Foods (Basel, Switzerland) · 2019Review
- Microglia Promote Increased Pain Behavior through Enhanced Inflammation in the Spinal Cord during Repeated Social Defeat Stress.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2019Article
- Effect of cannabidiolic acid and ∆Psychopharmacology · 2018Article
- Ropivacaine and Bupivacaine prevent increased pain sensitivity without altering neuroimmune activation following repeated social defeat stress.Brain, behavior, and immunity · 2018Article
- Partner Loss in Monogamous Rodents: Modulation of Pain and Emotional Behavior in Male Prairie Voles.Psychosomatic medicine · 2018Article
- The effect of repeated restraint stress in pain-related behavior induced by nucleus pulposus applied on the nerve root in rats.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2011Article
- Psychological stress induces temporary masticatory muscle mechanical sensitivity in rats.Journal of biomedicine & biotechnology · 2011Article
- Sensory stimulation prior to spinal cord injury induces post-injury dysesthesia in mice.Journal of neurotrauma · 2010Article
- Stress exacerbates neuropathic pain via glucocorticoid and NMDA receptor activation.Brain, behavior, and immunity · 2009Article
- Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Results were obtained from comparative studies of skin pain sensitivity (pain thresholds) using focused ultrasound in 51 healthy men and 101 patients with neurasthenia. Neurasthenia is a natural "model" of chronic psychoemotional stress, and patients showed a reduction in the pain threshold which was not accompanied by a reduction in the threshold of sensitivity to tactile stimulation. A reduction in the pain threshold, reflecting a weakening of central descending tonic inhibition, was probably due to a reduction in the activity of the brain's opioid system during long-term psychoemotional stress. Analysis of the relationships between the pain sensitivity threshold and pain syndromes suggests a role for changes in the nociception system in chronic psychoemotional stress, as part of the mechanism of pain formation.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.